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[[Image:1bru.jpg|left|200px]]


{{Structure
==STRUCTURE OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH THE ELASTASE INHIBITOR GR143783==
|PDB= 1bru |SIZE=350|CAPTION= <scene name='initialview01'>1bru</scene>, resolution 2.3&Aring;
<StructureSection load='1bru' size='340' side='right'caption='[[1bru]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
|SITE= <scene name='pdbsite=CAT:Catalytic+Triad'>CAT</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=1NB:2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL'>1NB</scene>
<table><tr><td colspan='2'>[[1bru]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BRU FirstGlance]. <br>
|ACTIVITY= [http://en.wikipedia.org/wiki/Pancreatic_elastase_II Pancreatic elastase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.71 3.4.21.71]  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
|GENE=  
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1NB:2-(2-HYDROXY-CYCLOPENTYL)-PENT-4-ENAL'>1NB</scene></td></tr>
}}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bru FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bru OCA], [https://pdbe.org/1bru PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bru RCSB], [https://www.ebi.ac.uk/pdbsum/1bru PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bru ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CEL2A_PIG CEL2A_PIG] Acts upon elastin.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/br/1bru_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bru ConSurf].
<div style="clear:both"></div>


'''STRUCTURE OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH THE ELASTASE INHIBITOR GR143783'''
==See Also==
 
*[[Elastase 3D structures|Elastase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
1BRU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BRU OCA].
[[Category: Large Structures]]
[[Category: Pancreatic elastase II]]
[[Category: Single protein]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Jhoti, H.]]
[[Category: Jhoti H]]
[[Category: Singh, O M.P.]]
[[Category: Singh OMP]]
[[Category: Wonacott, A.]]
[[Category: Wonacott A]]
[[Category: 1NB]]
[[Category: hydrolase]]
[[Category: serine protease]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 10:15:01 2008''

Latest revision as of 07:18, 23 October 2024

STRUCTURE OF PORCINE PANCREATIC ELASTASE COMPLEXED WITH THE ELASTASE INHIBITOR GR143783

1bru, resolution 2.30Å

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