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==THE CRYSTAL STRUCTURE OF A LYSINE 49 PHOSPHOLIPASE A2 FROM THE VENOM OF THE COTTONMOUTH SNAKE AT 2.0 ANGSTROMS RESOLUTION==
==THE CRYSTAL STRUCTURE OF A LYSINE 49 PHOSPHOLIPASE A2 FROM THE VENOM OF THE COTTONMOUTH SNAKE AT 2.0 ANGSTROMS RESOLUTION==
<StructureSection load='1ppa' size='340' side='right' caption='[[1ppa]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1ppa' size='340' side='right'caption='[[1ppa]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ppa]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Agkpi Agkpi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PPA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1PPA FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ppa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agkistrodon_piscivorus_piscivorus Agkistrodon piscivorus piscivorus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PPA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PPA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANL:ANILINE'>ANL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phospholipase_A(2) Phospholipase A(2)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.4 3.1.1.4] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANL:ANILINE'>ANL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ppa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ppa OCA], [http://pdbe.org/1ppa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ppa RCSB], [http://www.ebi.ac.uk/pdbsum/1ppa PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ppa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ppa OCA], [https://pdbe.org/1ppa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ppa RCSB], [https://www.ebi.ac.uk/pdbsum/1ppa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ppa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PA2HB_AGKPI PA2HB_AGKPI]] Snake venom phospholipase A2 (PLA2) that lacks enzymatic activity, but displays edema-inducing activities.<ref>PMID:1429612</ref>
[https://www.uniprot.org/uniprot/PA2HB_AGKPI PA2HB_AGKPI] Snake venom phospholipase A2 (PLA2) that lacks enzymatic activity, but displays edema-inducing activities.<ref>PMID:1429612</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pp/1ppa_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pp/1ppa_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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==See Also==
==See Also==
*[[Phospholipase A2|Phospholipase A2]]
*[[Phospholipase A2 3D structures|Phospholipase A2 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Agkpi]]
[[Category: Agkistrodon piscivorus piscivorus]]
[[Category: Clancy, L L]]
[[Category: Large Structures]]
[[Category: Einspahr, H M]]
[[Category: Clancy LL]]
[[Category: Finzel, B C]]
[[Category: Einspahr HM]]
[[Category: Heinrikson, R L]]
[[Category: Finzel BC]]
[[Category: Holland, D R]]
[[Category: Heinrikson RL]]
[[Category: Muchmore, S W]]
[[Category: Holland DR]]
[[Category: Rydel, T J]]
[[Category: Muchmore SW]]
[[Category: Watenpaugh, K D]]
[[Category: Rydel TJ]]
[[Category: Watenpaugh KD]]
Retrieved from "https://proteopedia.org/1ppa"