1rhd: Difference between revisions

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New page: left|200px<br /><applet load="1rhd" size="450" color="white" frame="true" align="right" spinBox="true" caption="1rhd, resolution 2.5Å" /> '''STRUCTURE OF BOVINE L...
 
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[[Image:1rhd.gif|left|200px]]<br /><applet load="1rhd" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1rhd, resolution 2.5&Aring;" />
'''STRUCTURE OF BOVINE LIVER RHODANESE. I. STRUCTURE DETERMINATION AT 2.5 ANGSTROMS RESOLUTION AND A COMPARISON OF THE CONFORMATION AND SEQUENCE OF ITS TWO DOMAINS'''<br />


==About this Structure==
==STRUCTURE OF BOVINE LIVER RHODANESE. I. STRUCTURE DETERMINATION AT 2.5 ANGSTROMS RESOLUTION AND A COMPARISON OF THE CONFORMATION AND SEQUENCE OF ITS TWO DOMAINS==
1RHD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with S as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Thiosulfate_sulfurtransferase Thiosulfate sulfurtransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.1 2.8.1.1] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1RHD OCA].  
<StructureSection load='1rhd' size='340' side='right'caption='[[1rhd]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1rhd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RHD FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rhd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rhd OCA], [https://pdbe.org/1rhd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rhd RCSB], [https://www.ebi.ac.uk/pdbsum/1rhd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rhd ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/THTR_BOVIN THTR_BOVIN] Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA (By similarity). Formation of iron-sulfur complexes and cyanide detoxification. Binds molecular oxygen and sulfur.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rh/1rhd_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rhd ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
Structure of bovine liver rhodanese. I. Structure determination at 2.5 A resolution and a comparison of the conformation and sequence of its two domains., Ploegman JH, Drent G, Kalk KH, Hol WG, J Mol Biol. 1978 Aug 25;123(4):557-94. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=691057 691057]
*[[Sulfurtransferase|Sulfurtransferase]]
__TOC__
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Thiosulfate sulfurtransferase]]
[[Category: Drent G]]
[[Category: Drent, G.]]
[[Category: Hol WGJ]]
[[Category: Hol, W.G.J.]]
[[Category: Kalk KH]]
[[Category: Kalk, K.H.]]
[[Category: Ploegman JH]]
[[Category: Ploegman, J.H.]]
[[Category: S]]
[[Category: cyanide sulfur)]]
[[Category: transferase(thiosulfate]]
 
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