2vxs: Difference between revisions
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<StructureSection load='2vxs' size='340' side='right'caption='[[2vxs]], [[Resolution|resolution]] 2.63Å' scene=''> | <StructureSection load='2vxs' size='340' side='right'caption='[[2vxs]], [[Resolution|resolution]] 2.63Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2vxs]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2vxs]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VXS FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.63Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vxs OCA], [https://pdbe.org/2vxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vxs RCSB], [https://www.ebi.ac.uk/pdbsum/2vxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vxs ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vxs OCA], [https://pdbe.org/2vxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vxs RCSB], [https://www.ebi.ac.uk/pdbsum/2vxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vxs ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/IL17_HUMAN IL17_HUMAN] Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vx/2vxs_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vx/2vxs_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Abbott | [[Category: Abbott WM]] | ||
[[Category: Aziz | [[Category: Aziz A]] | ||
[[Category: Barker | [[Category: Barker W]] | ||
[[Category: Bell | [[Category: Bell P]] | ||
[[Category: Coales | [[Category: Coales SJ]] | ||
[[Category: Davies | [[Category: Davies RA]] | ||
[[Category: Dawson | [[Category: Dawson S]] | ||
[[Category: Gerhardt | [[Category: Gerhardt S]] | ||
[[Category: Hamuro | [[Category: Hamuro Y]] | ||
[[Category: Hargreaves | [[Category: Hargreaves D]] | ||
[[Category: Langham | [[Category: Langham C]] | ||
[[Category: Needham | [[Category: Needham MRC]] | ||
[[Category: Pauptit | [[Category: Pauptit RA]] | ||
[[Category: Russell | [[Category: Russell C]] | ||
[[Category: Smith | [[Category: Smith MJ]] | ||
[[Category: Tuske | [[Category: Tuske SJ]] | ||
[[Category: Welsh | [[Category: Welsh F]] | ||
