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[[Image:4ull.png|left|200px]]


{{STRUCTURE_4ull|  PDB=4ull  |  SCENE=  }}
==SOLUTION NMR STRUCTURE OF VEROTOXIN-1 B-SUBUNIT FROM E. COLI, 5 STRUCTURES==
 
<StructureSection load='4ull' size='340' side='right'caption='[[4ull]]' scene=''>
===SOLUTION NMR STRUCTURE OF VEROTOXIN-1 B-SUBUNIT FROM E. COLI, 5 STRUCTURES===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4ull]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ULL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ULL FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 5 models</td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ull FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ull OCA], [https://pdbe.org/4ull PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ull RCSB], [https://www.ebi.ac.uk/pdbsum/4ull PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ull ProSAT]</span></td></tr>
[[4ull]] is a 1 chain structure of [[Shiga toxin]] with sequence from [http://en.wikipedia.org/wiki/Phage_h30,_enterobacteria_phage_h-19b Phage h30, enterobacteria phage h-19b]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ULL OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/STXB_BPH19 STXB_BPH19] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ul/4ull_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=4ull ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Shiga toxin|Shiga toxin]]
*[[Shiga toxin 3D structures|Shiga toxin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:009164458</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Phage h30, enterobacteria phage h-19b]]
[[Category: Large Structures]]
[[Category: Donohue-Rolfe, A.]]
[[Category: Donohue-Rolfe A]]
[[Category: Evans, P D.]]
[[Category: Evans PD]]
[[Category: Homans, S W.]]
[[Category: Homans SW]]
[[Category: Richardson, J M.]]
[[Category: Richardson JM]]
[[Category: Toxin]]

Latest revision as of 08:30, 23 October 2024

SOLUTION NMR STRUCTURE OF VEROTOXIN-1 B-SUBUNIT FROM E. COLI, 5 STRUCTURES

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