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==Crystal Structure Of The Fab Fragment of Esterolytic Antibody MS5-393==
==Crystal Structure Of The Fab Fragment of Esterolytic Antibody MS5-393==
<StructureSection load='1mie' size='340' side='right' caption='[[1mie]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='1mie' size='340' side='right'caption='[[1mie]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1mie]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MIE FirstGlance]. <br>
<table><tr><td colspan='2'>[[1mie]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MIE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MIE FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mh5|1mh5]], [[1mj7|1mj7]], [[1mj8|1mj8]], [[1mjj|1mjj]], [[1mju|1mju]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1mie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mie OCA], [http://pdbe.org/1mie PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1mie RCSB], [http://www.ebi.ac.uk/pdbsum/1mie PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1mie FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1mie OCA], [https://pdbe.org/1mie PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1mie RCSB], [https://www.ebi.ac.uk/pdbsum/1mie PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1mie ProSAT]</span></td></tr>
</table>
</table>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
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Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mie_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mi/1mie_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1mie ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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==See Also==
==See Also==
*[[Monoclonal Antibody|Monoclonal Antibody]]
*[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lk3 transgenic mice]]
[[Category: Large Structures]]
[[Category: Blackburn, G M]]
[[Category: Mus musculus]]
[[Category: Kakinuma, H]]
[[Category: Blackburn GM]]
[[Category: Muranova, T A]]
[[Category: Kakinuma H]]
[[Category: Murray, I A]]
[[Category: Muranova TA]]
[[Category: Nishi, Y]]
[[Category: Murray IA]]
[[Category: Partridge, L J]]
[[Category: Nishi Y]]
[[Category: Rice, D W]]
[[Category: Partridge LJ]]
[[Category: Ruzheinikov, S N]]
[[Category: Rice DW]]
[[Category: Sedelnikova, S E]]
[[Category: Ruzheinikov SN]]
[[Category: Shimazaki, K]]
[[Category: Sedelnikova SE]]
[[Category: Sun, J]]
[[Category: Shimazaki K]]
[[Category: Takashi, N]]
[[Category: Sun J]]
[[Category: Catalytic antibody]]
[[Category: Takashi N]]
[[Category: Ester hydrolysis]]
[[Category: Esterolytic]]
[[Category: Fab]]
[[Category: Immune system]]
[[Category: Immunoglobulin]]
Retrieved from "https://proteopedia.org/1mie"