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[[Image:2nrj.gif|left|200px]]
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{{STRUCTURE_2nrj|  PDB=2nrj  |  SCENE=  }}
'''Crystal Structure of Hemolysin binding component from Bacillus cereus'''


==Crystal Structure of Hemolysin binding component from Bacillus cereus==
<StructureSection load='2nrj' size='340' side='right'caption='[[2nrj]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NRJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NRJ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nrj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nrj OCA], [https://pdbe.org/2nrj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nrj RCSB], [https://www.ebi.ac.uk/pdbsum/2nrj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nrj ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/2nrj TOPSAN]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nr/2nrj_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2nrj ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Bacillus cereus Hemolysin BL enterotoxin, a ternary complex of three proteins, is the causative agent of food poisoning and requires all three components for virulence. The X-ray structure of the binding domain of HBL suggests that it may form a pore similar to other soluble channel forming proteins. A putative pathway of pore formation is discussed.


==Overview==
X-ray crystal structure of the B component of Hemolysin BL from Bacillus cereus.,Madegowda M, Eswaramoorthy S, Burley SK, Swaminathan S Proteins. 2008 May 1;71(2):534-40. PMID:18175317<ref>PMID:18175317</ref>
Bacillus cereus Hemolysin BL enterotoxin, a ternary complex of three proteins, is the causative agent of food poisoning and requires all three components for virulence. The X-ray structure of the binding domain of HBL suggests that it may form a pore similar to other soluble channel forming proteins. A putative pathway of pore formation is discussed.


==About this Structure==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
2NRJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NRJ OCA].
</div>
<div class="pdbe-citations 2nrj" style="background-color:#fffaf0;"></div>


==Reference==
==See Also==
X-ray crystal structure of the B component of Hemolysin BL from Bacillus cereus., Madegowda M, Eswaramoorthy S, Burley SK, Swaminathan S, Proteins. 2008 May 1;71(2):534-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18175317 18175317]
*[[Hemolysin 3D structures|Hemolysin 3D structures]]
[[Category: Bacillus cereus]]
== References ==
[[Category: Single protein]]
<references/>
[[Category: Burley, S K.]]
__TOC__
[[Category: Eswaramoorthy, S.]]
</StructureSection>
[[Category: Madegowda, M.]]
[[Category: Large Structures]]
[[Category: NYSGXRC, New York Structural GenomiX Research Consortium.]]
[[Category: Burley SK]]
[[Category: Swaminathan, S.]]
[[Category: Eswaramoorthy S]]
[[Category: Enterotoxin]]
[[Category: Madegowda M]]
[[Category: Hemolysis]]
[[Category: Swaminathan S]]
[[Category: New york structural genomix research consortium]]
[[Category: Nysgxrc]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: Transmembrane]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 30 13:29:33 2008''

Latest revision as of 08:21, 30 October 2024

Crystal Structure of Hemolysin binding component from Bacillus cereus

2nrj, resolution 2.03Å

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