2roo: Difference between revisions
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New page: '''Unreleased structure''' The entry 2roo is ON HOLD until Paper Publication Authors: Yamaji, N., Nishio, H., Villegas, E., Nishiuchi, Y., Corzo, G. Description: Solution structure of ... |
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==Solution structure of Magi4, a spider toxin from Macrothele gigas== | |||
<StructureSection load='2roo' size='340' side='right'caption='[[2roo]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2roo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Macrothele_gigas Macrothele gigas]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ROO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ROO FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2roo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2roo OCA], [https://pdbe.org/2roo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2roo RCSB], [https://www.ebi.ac.uk/pdbsum/2roo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2roo ProSAT]</span></td></tr> | |||
</table> | |||
'' | == Function == | ||
[https://www.uniprot.org/uniprot/TXMG4_MACGS TXMG4_MACGS] Selectively slows channel inactivation of mammalian Nav1.1/SCN1A, Nav1.3/SCN3A, and Nav1.6/SCN8A and shows higher affinity for insect Nav1/para channels (site 3). Induces tonic repetitive firing of nerve impulses in insect neurons accompanied by plateau potentials.<ref>PMID:12860384</ref> <ref>PMID:19592486</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Macrothele gigas]] | |||
[[Category: Yamaji N]] | |||
Latest revision as of 08:39, 30 October 2024
Solution structure of Magi4, a spider toxin from Macrothele gigas
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