3hcv: Difference between revisions

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New page: '''Unreleased structure''' The entry 3hcv is ON HOLD Authors: Beltrami A., Rossmann M., Gabdulkhakov, A., Ziegler A., Uchanska-Ziegler B., Saenger W. Description: CRYSTAL STRUCTURE OF ...
 
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'''Unreleased structure'''


The entry 3hcv is ON HOLD
==Crystal structure of HLA-B*2709 complexed with the double citrullinated vasoactive intestinal peptide type 1 receptor (VIPR) peptide (residues 400-408)==
<StructureSection load='3hcv' size='340' side='right'caption='[[3hcv]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3hcv]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HCV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HCV FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIR:CITRULLINE'>CIR</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hcv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hcv OCA], [https://pdbe.org/3hcv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hcv RCSB], [https://www.ebi.ac.uk/pdbsum/3hcv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hcv ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VIPR1_HUMAN VIPR1_HUMAN] This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38.<ref>PMID:8926282</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hc/3hcv_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hcv ConSurf].
<div style="clear:both"></div>


Authors: Beltrami A., Rossmann M., Gabdulkhakov, A., Ziegler A., Uchanska-Ziegler B., Saenger W.
==See Also==
 
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
Description: CRYSTAL STRUCTURE OF HLA-B*2709 COMPLEXED WITH THE DOUBLE CITRULLINATED VASOACTIVE INTESTINAL PEPTIDE TYPE 1 RECEPTOR (VIPR) PEPTIDE (RESIDUES 400-408)
*[[MHC 3D structures|MHC 3D structures]]
 
*[[MHC I 3D structures|MHC I 3D structures]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 13 09:38:21 2009''
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Beltrami A]]
[[Category: Gabdulkhakov A]]
[[Category: Rossmann M]]
[[Category: Saenger W]]
[[Category: Uchanska-Ziegler B]]
[[Category: Ziegler A]]