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[[Image:2exr.gif|left|200px]]


{{Structure
==X-Ray Structure of Cytokinin Oxidase/Dehydrogenase (CKX) From Arabidopsis Thaliana AT5G21482==
|PDB= 2exr |SIZE=350|CAPTION= <scene name='initialview01'>2exr</scene>, resolution 1.702&Aring;
<StructureSection load='2exr' size='340' side='right'caption='[[2exr]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
|SITE= <scene name='pdbsite=AC1:Fad+Binding+Site+For+Residue+A+525'>AC1</scene>
== Structural highlights ==
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
<table><tr><td colspan='2'>[[2exr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EXR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EXR FirstGlance]. <br>
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytokinin_dehydrogenase Cytokinin dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.99.12 1.5.99.12] </span>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.702&#8491;</td></tr>
|GENE= CKX7, CKX5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 Arabidopsis thaliana])
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam09265 Cytokin-bind], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam01565 FAD_binding_4]</span>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2exr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2exr OCA], [https://pdbe.org/2exr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2exr RCSB], [https://www.ebi.ac.uk/pdbsum/2exr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2exr ProSAT], [https://www.topsan.org/Proteins/CESG/2exr TOPSAN]</span></td></tr>
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2exr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2exr OCA], [http://www.ebi.ac.uk/pdbsum/2exr PDBsum], [http://www.fli-leibniz.de/cgi-bin/ImgLib.pl?CODE=1kfv JenaLib], [http://www.rcsb.org/pdb/explore.do?structureId=2exr RCSB]</span>
</table>
}}
== Function ==
 
[https://www.uniprot.org/uniprot/CKX7_ARATH CKX7_ARATH] Catalyzes the oxidation of cytokinins, a family of N(6)-substituted adenine derivatives that are plant hormones, where the substituent is an isopentenyl group (By similarity).
'''X-Ray Structure of Cytokinin Oxidase/Dehydrogenase (CKX) From Arabidopsis Thaliana AT5G21482'''
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
 
Check<jmol>
==About this Structure==
  <jmolCheckbox>
2EXR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EXR OCA].  
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ex/2exr_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2exr ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Cytokinin dehydrogenase]]
[[Category: Large Structures]]
[[Category: Single protein]]
[[Category: Bae E]]
[[Category: Bae, E.]]
[[Category: Bingman CA]]
[[Category: Bingman, C A.]]
[[Category: Bitto E]]
[[Category: Bitto, E.]]
[[Category: Han BW]]
[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
[[Category: Phillips Jr GN]]
[[Category: Han, B W.]]
[[Category: Wesenberg GE]]
[[Category: Jr., G N.Phillips.]]
[[Category: Wesenberg, G E.]]
[[Category: at5g21482 1]]
[[Category: center for eukaryotic structural genomic]]
[[Category: cesg]]
[[Category: ckx]]
[[Category: cytokinin oxidase/dehydrogenase]]
[[Category: oxidoreductase]]
[[Category: protein structure initiative]]
[[Category: psi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 26 06:23:22 2008''

Latest revision as of 09:06, 6 November 2024

X-Ray Structure of Cytokinin Oxidase/Dehydrogenase (CKX) From Arabidopsis Thaliana AT5G21482

2exr, resolution 1.70Å

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