2m96: Difference between revisions

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==Solution NMR structure of the RXFP2 LDLa module==
==Solution NMR structure of the RXFP2 LDLa module==
<StructureSection load='2m96' size='340' side='right' caption='[[2m96]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2m96' size='340' side='right'caption='[[2m96]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2m96]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M96 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2M96 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2m96]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M96 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2m96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m96 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2m96 RCSB], [http://www.ebi.ac.uk/pdbsum/2m96 PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m96 OCA], [https://pdbe.org/2m96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m96 RCSB], [https://www.ebi.ac.uk/pdbsum/2m96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m96 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/RXFP2_HUMAN RXFP2_HUMAN]] The disease is caused by mutations affecting the gene represented in this entry.  
[https://www.uniprot.org/uniprot/RXFP2_HUMAN RXFP2_HUMAN] The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RXFP2_HUMAN RXFP2_HUMAN]] Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).  
[https://www.uniprot.org/uniprot/RXFP2_HUMAN RXFP2_HUMAN] Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bathgate, A D]]
[[Category: Homo sapiens]]
[[Category: Gooley, P R]]
[[Category: Large Structures]]
[[Category: Petrie, E J]]
[[Category: Bathgate AD]]
[[Category: Insl3 receptor]]
[[Category: Gooley PR]]
[[Category: Membrane protein]]
[[Category: Petrie EJ]]
[[Category: Signaling]]

Latest revision as of 09:18, 6 November 2024

Solution NMR structure of the RXFP2 LDLa module

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