2oqf: Difference between revisions
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< | ==Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A== | ||
<StructureSection load='2oqf' size='340' side='right'caption='[[2oqf]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2oqf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OQF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OQF FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=XX1:N~6~-7H-PURIN-6-YL-L-LYSINE'>XX1</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2oqf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2oqf OCA], [https://pdbe.org/2oqf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2oqf RCSB], [https://www.ebi.ac.uk/pdbsum/2oqf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2oqf ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/oq/2oqf_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2oqf ConSurf]. | |||
<div style="clear:both"></div> | |||
=== | ==See Also== | ||
*[[Ribonuclease 3D structures|Ribonuclease 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
[[Category: | </StructureSection> | ||
[[Category: Boerema | [[Category: Bos taurus]] | ||
[[Category: He | [[Category: Large Structures]] | ||
[[Category: Kent | [[Category: Boerema DJ]] | ||
[[Category: Tereshko | [[Category: He C]] | ||
[[Category: Zhang | [[Category: Kent SBH]] | ||
[[Category: Tereshko VA]] | |||
[[Category: Zhang JL]] | |||
Latest revision as of 09:24, 6 November 2024
Structure of a synthetic, non-natural analogue of RNase A: [N71K(Ade), D83A]RNase A
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