2r7f: Difference between revisions

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==Crystal structure of ribonuclease II family protein from Deinococcus radiodurans, hexagonal crystal form. NorthEast Structural Genomics target DrR63==
==Crystal structure of ribonuclease II family protein from Deinococcus radiodurans, hexagonal crystal form. NorthEast Structural Genomics target DrR63==
<StructureSection load='2r7f' size='340' side='right' caption='[[2r7f]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='2r7f' size='340' side='right'caption='[[2r7f]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2r7f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans_r1 Deinococcus radiodurans r1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R7F OCA]. <br>
<table><tr><td colspan='2'>[[2r7f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R7F FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2r7d|2r7d]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DR_0020 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243230 Deinococcus radiodurans R1])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r7f OCA], [https://pdbe.org/2r7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r7f RCSB], [https://www.ebi.ac.uk/pdbsum/2r7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r7f ProSAT], [https://www.topsan.org/Proteins/NESGC/2r7f TOPSAN]</span></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
</table>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2r7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r7f OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2r7f RCSB], [http://www.ebi.ac.uk/pdbsum/2r7f PDBsum], [http://www.topsan.org/Proteins/NESGC/2r7f TOPSAN]</span></td></tr>
== Function ==
<table>
[https://www.uniprot.org/uniprot/Q9RYD0_DEIRA Q9RYD0_DEIRA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r7/2r7f_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r7/2r7f_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r7f ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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The Structure and Enzymatic Properties of a Novel RNase II Family Enzyme from Deinococcus radiodurans.,Schmier BJ, Seetharaman J, Deutscher MP, Hunt JF, Malhotra A J Mol Biol. 2011 Nov 23. PMID:22133431<ref>PMID:22133431</ref>
The Structure and Enzymatic Properties of a Novel RNase II Family Enzyme from Deinococcus radiodurans.,Schmier BJ, Seetharaman J, Deutscher MP, Hunt JF, Malhotra A J Mol Biol. 2011 Nov 23. PMID:22133431<ref>PMID:22133431</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2r7f" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Deinococcus radiodurans r1]]
[[Category: Deinococcus radiodurans R1]]
[[Category: Acton, T B.]]
[[Category: Large Structures]]
[[Category: Baran, M C.]]
[[Category: Acton TB]]
[[Category: Cunningham, K.]]
[[Category: Baran MC]]
[[Category: Fang, Y.]]
[[Category: Cunningham K]]
[[Category: Forouhar, F.]]
[[Category: Fang Y]]
[[Category: Hunt, J F.]]
[[Category: Forouhar F]]
[[Category: Liu, J.]]
[[Category: Hunt JF]]
[[Category: Ma, L-C.]]
[[Category: Liu J]]
[[Category: Montelione, G T.]]
[[Category: Ma L-C]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Montelione GT]]
[[Category: Neely, H.]]
[[Category: Neely H]]
[[Category: Rost, B.]]
[[Category: Rost B]]
[[Category: Seetharaman, J.]]
[[Category: Seetharaman J]]
[[Category: Tong, L.]]
[[Category: Tong L]]
[[Category: Wang, D.]]
[[Category: Wang D]]
[[Category: Xia, R.]]
[[Category: Xia R]]
[[Category: Hydrolase]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Ribonuclease ii family protein]]
[[Category: Structural genomic]]