1c48: Difference between revisions

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New page: left|200px<br /><applet load="1c48" size="450" color="white" frame="true" align="right" spinBox="true" caption="1c48, resolution 1.60Å" /> '''MUTATED SHIGA-LIKE T...
 
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[[Image:1c48.gif|left|200px]]<br /><applet load="1c48" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1c48, resolution 1.60&Aring;" />
'''MUTATED SHIGA-LIKE TOXIN B SUBUNIT (G62T)'''<br />


==About this Structure==
==MUTATED SHIGA-LIKE TOXIN B SUBUNIT (G62T)==
1C48 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_pyogenes_phage_h4489a Streptococcus pyogenes phage h4489a]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1C48 OCA].  
<StructureSection load='1c48' size='340' side='right'caption='[[1c48]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
[[Category: Single protein]]
== Structural highlights ==
[[Category: Streptococcus pyogenes phage h4489a]]
<table><tr><td colspan='2'>[[1c48]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Phage_h30 Phage h30]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C48 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C48 FirstGlance]. <br>
[[Category: Bast, D.]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
[[Category: Brunton, J.L.]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c48 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c48 OCA], [https://pdbe.org/1c48 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c48 RCSB], [https://www.ebi.ac.uk/pdbsum/1c48 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c48 ProSAT]</span></td></tr>
[[Category: Ling, H.]]
</table>
[[Category: Read, R.J.]]
== Function ==
[[Category: ob-fold]]
[https://www.uniprot.org/uniprot/STXB_BPH30 STXB_BPH30] The B subunit is responsible for the binding of the holotoxin to specific receptors on the target cell surface, such as globotriaosylceramide (Gb3) in human intestinal microvilli.
[[Category: protein-carbohydrate recognition]]
== Evolutionary Conservation ==
[[Category: receptor binding]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: toxin]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c4/1c48_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1c48 ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Nov 20 12:08:44 2007''
==See Also==
*[[Shiga toxin 3D structures|Shiga toxin 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Phage h30]]
[[Category: Bast D]]
[[Category: Brunton JL]]
[[Category: Ling H]]
[[Category: Read RJ]]