1m4k: Difference between revisions

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==Crystal structure of the human natural killer cell activator receptor KIR2DS2 (CD158j)==
==Crystal structure of the human natural killer cell activator receptor KIR2DS2 (CD158j)==
<StructureSection load='1m4k' size='340' side='right' caption='[[1m4k]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='1m4k' size='340' side='right'caption='[[1m4k]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1m4k]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M4K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1M4K FirstGlance]. <br>
<table><tr><td colspan='2'>[[1m4k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M4K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1M4K FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1m4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m4k OCA], [http://pdbe.org/1m4k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1m4k RCSB], [http://www.ebi.ac.uk/pdbsum/1m4k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1m4k ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1m4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1m4k OCA], [https://pdbe.org/1m4k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1m4k RCSB], [https://www.ebi.ac.uk/pdbsum/1m4k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1m4k ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KI2S2_HUMAN KI2S2_HUMAN]] Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.  
[https://www.uniprot.org/uniprot/KI2S2_HUMAN KI2S2_HUMAN] Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m4/1m4k_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m4/1m4k_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Gastinel, L N]]
[[Category: Large Structures]]
[[Category: Saulquin, X]]
[[Category: Gastinel LN]]
[[Category: Vivier, E]]
[[Category: Saulquin X]]
[[Category: Beta-sandwich]]
[[Category: Vivier E]]
[[Category: Ig-like c2 type domain]]
[[Category: Immune system]]

Latest revision as of 00:14, 21 November 2024

Crystal structure of the human natural killer cell activator receptor KIR2DS2 (CD158j)

1m4k, resolution 2.30Å

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