2axe: Difference between revisions

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==IODINATED COMPLEX OF ACETYL XYLAN ESTERASE AT 1.80 ANGSTROMS==
==IODINATED COMPLEX OF ACETYL XYLAN ESTERASE AT 1.80 ANGSTROMS==
<StructureSection load='2axe' size='340' side='right' caption='[[2axe]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='2axe' size='340' side='right'caption='[[2axe]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2axe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Penicillium_purpurogenum Penicillium purpurogenum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AXE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2AXE FirstGlance]. <br>
<table><tr><td colspan='2'>[[2axe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Talaromyces_purpureogenus Talaromyces purpureogenus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AXE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2AXE FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TYI:3,5-DIIODOTYROSINE'>TYI</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TYI:3,5-DIIODOTYROSINE'>TYI</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylesterase Acetylesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.6 3.1.1.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2axe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2axe OCA], [https://pdbe.org/2axe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2axe RCSB], [https://www.ebi.ac.uk/pdbsum/2axe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2axe ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2axe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2axe OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2axe RCSB], [http://www.ebi.ac.uk/pdbsum/2axe PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/AXE2_TALPU AXE2_TALPU] Degrades acetylated xylans by cleaving acetyl side groups from the hetero-xylan backbone.<ref>PMID:8756392</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ax/2axe_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ax/2axe_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2axe ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2axe" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
*[[Acetylxylan esterase|Acetylxylan esterase]]
*[[Acetylxylan esterase 3D structures|Acetylxylan esterase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Acetylesterase]]
[[Category: Large Structures]]
[[Category: Penicillium purpurogenum]]
[[Category: Talaromyces purpureogenus]]
[[Category: Erman, M.]]
[[Category: Erman M]]
[[Category: Eyzaguirre, J.]]
[[Category: Eyzaguirre J]]
[[Category: Ghosh, D.]]
[[Category: Ghosh D]]
[[Category: Jornvall, H.]]
[[Category: Jornvall H]]
[[Category: Lala, P.]]
[[Category: Lala P]]
[[Category: Li, N.]]
[[Category: Li N]]
[[Category: Pangborn, W.]]
[[Category: Pangborn W]]
[[Category: Sawicki, M W.]]
[[Category: Sawicki MW]]
[[Category: Thiel, D J.]]
[[Category: Thiel DJ]]
[[Category: Weeks, D R.]]
[[Category: Weeks DR]]
[[Category: Esterase]]
[[Category: Hydrolase]]
[[Category: Iodotyrosine]]