2n6f: Difference between revisions
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==Structure of Pleiotrophin== | ==Structure of Pleiotrophin== | ||
<StructureSection load='2n6f' size='340' side='right' caption='[[2n6f | <StructureSection load='2n6f' size='340' side='right'caption='[[2n6f]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2n6f]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6F OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[2n6f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2N6F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2N6F FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 10 models</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2n6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2n6f OCA], [https://pdbe.org/2n6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2n6f RCSB], [https://www.ebi.ac.uk/pdbsum/2n6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2n6f ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PTN_HUMAN PTN_HUMAN] Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation.<ref>PMID:11278720</ref> <ref>PMID:1768439</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Ryan EO]] | ||
[[Category: | [[Category: Shen D]] | ||
[[Category: | [[Category: Wang X]] | ||