4ct3: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(One intermediate revision by the same user not shown)
Line 3: Line 3:
<StructureSection load='4ct3' size='340' side='right'caption='[[4ct3]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
<StructureSection load='4ct3' size='340' side='right'caption='[[4ct3]], [[Resolution|resolution]] 1.69&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ct3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bppgk Bppgk]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CT3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CT3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ct3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_virus_K Staphylococcus virus K]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CT3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CT3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CMH:S-(METHYLMERCURY)-L-CYSTEINE'>CMH</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MMC:METHYL+MERCURY+ION'>MMC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.69&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4csh|4csh]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CMH:S-(METHYLMERCURY)-L-CYSTEINE'>CMH</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=MMC:METHYL+MERCURY+ION'>MMC</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ct3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ct3 OCA], [http://pdbe.org/4ct3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ct3 RCSB], [http://www.ebi.ac.uk/pdbsum/4ct3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ct3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ct3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ct3 OCA], [https://pdbe.org/4ct3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ct3 RCSB], [https://www.ebi.ac.uk/pdbsum/4ct3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ct3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ENLYS_BPPGK ENLYS_BPPGK] Endolysin that degrades host peptidoglycans and participates in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles (Probable). Exhibits lytic activity against Staphylococcus aureus (PubMed:19493008, PubMed:25064136). The CHAP activity cleaves the peptidic bond between the D-alanine of the tetra-peptide stem and the first glycine of the penta-glycine cross-bridge (PubMed:19493008, PubMed:25064136). The N-acetyl-muramidase activity cleaves between N-acetylmuramic acid and N-acetylglucosamine bonds (PubMed:19493008).<ref>PMID:19493008</ref> <ref>PMID:25064136</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 21: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bppgk]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Coffey, A]]
[[Category: Staphylococcus virus K]]
[[Category: Garcia-Doval, C]]
[[Category: Coffey A]]
[[Category: Keary, R]]
[[Category: Garcia-Doval C]]
[[Category: Raaij, M J.van]]
[[Category: Keary R]]
[[Category: Sanz-Gaitero, M]]
[[Category: Sanz-Gaitero M]]
[[Category: Peptidoglycan]]
[[Category: Van Raaij MJ]]
[[Category: Protease]]
[[Category: Viral protein]]
Retrieved from "https://proteopedia.org/4ct3"