5l6f: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:


==Xylooligosaccharide oxidase from Myceliophthora thermophila C1 in complex with Xylobiose==
==Xylooligosaccharide oxidase from Myceliophthora thermophila C1 in complex with Xylobiose==
<StructureSection load='5l6f' size='340' side='right' caption='[[5l6f]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='5l6f' size='340' side='right'caption='[[5l6f]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5l6f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L6F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L6F FirstGlance]. <br>
<table><tr><td colspan='2'>[[5l6f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermothelomyces_thermophilus_ATCC_42464 Thermothelomyces thermophilus ATCC 42464]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L6F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L6F FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BXP:4-O-BETA-D-XYLOPYRANOSYL-BETA-D-XYLOPYRANOSE'>BXP</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l6f OCA], [http://pdbe.org/5l6f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l6f RCSB], [http://www.ebi.ac.uk/pdbsum/5l6f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l6f ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l6f OCA], [https://pdbe.org/5l6f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l6f RCSB], [https://www.ebi.ac.uk/pdbsum/5l6f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l6f ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/XYLO_THET4 XYLO_THET4] Catalyzes the selective oxidation of C1 hydroxyl moieties on mono-, oligo- and polysaccharides with concomitant reduction of molecular oxygen to hydrogen peroxide. This results in the formation of the corresponding lactones, which typically undergo spontaneous hydrolysis. Xylooligosaccharide oxidase is able to oxidize a variety of substrates including D-xylose, D-cellobiose, lactose and arabinose. The enzyme acts primarily on xylooligosaccharides, indicating that it prefers pentose-based oligosaccharides over hexose-based oligosaccharides.<ref>PMID:27629413</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 20: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ferrari, A R]]
[[Category: Large Structures]]
[[Category: Fraaije, M W]]
[[Category: Thermothelomyces thermophilus ATCC 42464]]
[[Category: Rozeboom, H J]]
[[Category: Ferrari AR]]
[[Category: Cazy]]
[[Category: Fraaije MW]]
[[Category: Fad]]
[[Category: Rozeboom HJ]]
[[Category: Oligosaccharide]]
[[Category: Oxidoreductase]]
[[Category: Xylan]]
[[Category: Xylose]]