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[[Image:3fer.png|left|200px]]


{{STRUCTURE_3fer|  PDB=3fer  |  SCENE=  }}
==Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.==
 
<StructureSection load='3fer' size='340' side='right'caption='[[3fer]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
===Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3fer]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FER OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3FER FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
[[3fer]] is a 4 chain structure of [[Filamin]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3FER OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3fer FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3fer OCA], [https://pdbe.org/3fer PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3fer RCSB], [https://www.ebi.ac.uk/pdbsum/3fer PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3fer ProSAT], [https://www.topsan.org/Proteins/NESGC/3fer TOPSAN]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fe/3fer_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3fer ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Filamin|Filamin]]
*[[Filamin 3D structures|Filamin 3D structures]]
*[[User:Georg Mlynek/workbench|User:Georg Mlynek/workbench]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Abashidze, M.]]
[[Category: Large Structures]]
[[Category: Acton, T.]]
[[Category: Abashidze M]]
[[Category: Ciccosanti, C.]]
[[Category: Acton T]]
[[Category: Everett, J K.]]
[[Category: Ciccosanti C]]
[[Category: Huang, Y.]]
[[Category: Everett JK]]
[[Category: Hunt, J F.]]
[[Category: Huang Y]]
[[Category: Kuzin, A P.]]
[[Category: Hunt JF]]
[[Category: Montelione, G T.]]
[[Category: Kuzin AP]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Montelione GT]]
[[Category: Rost, B.]]
[[Category: Rost B]]
[[Category: Sahdev, S.]]
[[Category: Sahdev S]]
[[Category: Seetharaman, R.]]
[[Category: Seetharaman R]]
[[Category: Shastry, R.]]
[[Category: Shastry R]]
[[Category: Tong, L.]]
[[Category: Tong L]]
[[Category: Xiao, R.]]
[[Category: Xiao R]]
[[Category: Actin binding protein]]
[[Category: Actin-binding]]
[[Category: Cytoskeleton]]
[[Category: Developmental protein]]
[[Category: Differentiation]]
[[Category: Disease mutation]]
[[Category: Dwarfism]]
[[Category: Myogenesis]]
[[Category: Northeast structural genomics consortium]]
[[Category: Phosphoprotein]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
[[Category: X-ray nesg hr5571a actin-binding domain]]