4e74: Difference between revisions

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[[Image:4e74.jpg|left|200px]]


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==Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A==
The line below this paragraph, containing "STRUCTURE_4e74", creates the "Structure Box" on the page.
<StructureSection load='4e74' size='340' side='right'caption='[[4e74]], [[Resolution|resolution]] 1.58&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4e74]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E74 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E74 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.58&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e74 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e74 OCA], [https://pdbe.org/4e74 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e74 RCSB], [https://www.ebi.ac.uk/pdbsum/4e74 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e74 ProSAT]</span></td></tr>
{{STRUCTURE_4e74|  PDB=4e74  |  SCENE=  }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/PLXA4_HUMAN PLXA4_HUMAN] Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).


===Crystal structure of the RHO GTPASE BINDING DOMAIN of Plexin A4A===
==See Also==
 
*[[Plexin 3D structures|Plexin 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[4e74]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E74 OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Dong, A.]]
[[Category: Bountra C]]
[[Category: Edwards, A M.]]
[[Category: Dong A]]
[[Category: Guan, X.]]
[[Category: Edwards AM]]
[[Category: Park, H.]]
[[Category: Guan X]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Park H]]
[[Category: Tempel, W.]]
[[Category: Tempel W]]
[[Category: Tong, Y.]]
[[Category: Tong Y]]
[[Category: Wang, H.]]
[[Category: Wang H]]
[[Category: Weigelt, J.]]
[[Category: Weigelt J]]
[[Category: Plexin]]
[[Category: Rbd]]
[[Category: Sgc]]
[[Category: Signaling protein]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
Retrieved from "https://proteopedia.org/4e74"