3a30: Difference between revisions

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==E. coli Gsp amidase C59 acetate modification==
==E. coli Gsp amidase C59 acetate modification==
<StructureSection load='3a30' size='340' side='right' caption='[[3a30]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3a30' size='340' side='right'caption='[[3a30]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3a30]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3A30 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3a30]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A30 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A30 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2iob|2iob]], [[3a2y|3a2y]], [[3a2z|3a2z]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">gsp, b2988, JW2956 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a30 OCA], [https://pdbe.org/3a30 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a30 RCSB], [https://www.ebi.ac.uk/pdbsum/3a30 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a30 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3a30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a30 OCA], [http://pdbe.org/3a30 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3a30 RCSB], [http://www.ebi.ac.uk/pdbsum/3a30 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3a30 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/GSP_ECOLI GSP_ECOLI]] Catalyzes the formation of an amide bond between glutathione and spermidine coupled with hydrolysis of ATP; also catalyzes the hydrolysis of glutathionylspermidine to glutathione and spermidine.  
[https://www.uniprot.org/uniprot/GSP_ECOLI GSP_ECOLI] Catalyzes the formation of an amide bond between glutathione and spermidine coupled with hydrolysis of ATP; also catalyzes the hydrolysis of glutathionylspermidine to glutathione and spermidine.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a3/3a30_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a3/3a30_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Chiang, B Y]]
[[Category: Large Structures]]
[[Category: Ko, T P]]
[[Category: Chiang B-Y]]
[[Category: Lin, C H]]
[[Category: Ko T-P]]
[[Category: Pai, C H]]
[[Category: Lin C-H]]
[[Category: Wang, A H.J]]
[[Category: Pai C-H]]
[[Category: Atp-binding]]
[[Category: Wang AH-J]]
[[Category: Gsp amidase]]
[[Category: Hydrolase]]
[[Category: Ligase]]
[[Category: Multifunctional enzyme]]
[[Category: Nucleotide-binding]]