9be4: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "9be4" [edit=sysop:move=sysop] |
No edit summary |
||
| (One intermediate revision by the same user not shown) | |||
| Line 1: | Line 1: | ||
The | ==The post-condensation state of the dimodular NRPS protein LgrA== | ||
<StructureSection load='9be4' size='340' side='right'caption='[[9be4]], [[Resolution|resolution]] 3.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9be4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_parabrevis Brevibacillus parabrevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9BE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9BE4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4HH:O-[(S)-HYDROXY{[(3R)-3-HYDROXY-2,2-DIMETHYL-4-OXO-4-({3-OXO-3-[(2-SULFANYLETHYL)AMINO]PROPYL}AMINO)BUTYL]OXY}PHOSPHORYL]-L-SERINE'>4HH</scene>, <scene name='pdbligand=A1AMN:N-formyl-L-valyl-N-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]glycinamide'>A1AMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9be4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9be4 OCA], [https://pdbe.org/9be4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9be4 RCSB], [https://www.ebi.ac.uk/pdbsum/9be4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9be4 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LGRA_BREPA LGRA_BREPA] Activates valine (or leucine, but much less frequently), and then glycine and catalyzes the formation of the peptide bond in the first step of peptide synthesis. This enzyme may also play a role in N-formylation of the first amino acid residue in the synthesized dipeptide. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Brevibacillus parabrevis]] | |||
[[Category: Large Structures]] | |||
[[Category: Pistofidis A]] | |||
[[Category: Schmeing TM]] | |||
Latest revision as of 10:09, 25 December 2024
The post-condensation state of the dimodular NRPS protein LgrA
| ||||||||||||
