9dwm: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9dwm is ~~ON HOLD~~

==DNA polymerase Beta bound to a nucleosome containing a 1-nt gap at SHL-5.5==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9dwm]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DWM FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.2Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dwm OCA], [https://pdbe.org/9dwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dwm RCSB], [https://www.ebi.ac.uk/pdbsum/9dwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dwm ProSAT]</span></td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Synthetic construct]]

[[Category: Freudenthal BD]]

[[Category: Ryan BJ]]

[[Category: Weaver TM]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9dwm is ON HOLD
+==DNA polymerase Beta bound to a nucleosome containing a 1-nt gap at SHL-5.5==
+<StructureSection load='9dwm' size='340' side='right'caption='[[9dwm]], [[Resolution|resolution]] 4.20&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9dwm]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DWM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DWM FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.2&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9dwm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9dwm OCA], [https://pdbe.org/9dwm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9dwm RCSB], [https://www.ebi.ac.uk/pdbsum/9dwm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9dwm ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Synthetic construct]]
+[[Category: Freudenthal BD]]
+[[Category: Ryan BJ]]
+[[Category: Weaver TM]]