Complement C3 3D structures

3D structures of complement C3

Updated on 03-February-2025

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• Complement C3
  • 2a73 – hCC3 – human
    
  • 1ghq – hCC3 residues 996-1300 + Epstein-Barr virus receptor
    
  • 4zh1 – hCC3 + complement factor H
    
  • 7noz – hCC3 + complement factor B + complement factor P + properdin + nanobody
    
  • 7bag – hCC3 + compstatin CP40
    
  • 6ruv – hCC3 + complement factor B + complement factor H + nanobody + protein inhibitor
    
  • 6ru5 – hCC3 + nanobody
    
  • 8oq3 – hCC3 + nanobody – Cryo EM
    
  • 6s0b – hCC3 + properdin
    
  • 8cem – bCC3 – bovine
    
• Complement C3a (anaphylatoxin)
  • 4hw5, 4hwj, 4i6o – hCC3
    
• Complement C3b
  • 2i07, 5fo7 – hCC3 β+α’ chains
    
  • 5fob – hCC3 β+α’ chains + inhibitor
    
  • 5fo9 – hCC3 β+α’ chains + complement receptor
    
  • 8enu – hCC3 β+α’ chains + inhibitor protein
    
  • 7zgj, 7zgk, 8ovb, 8uh2, 8uin – hCC3 β+α’ chains + inhibitor protein – Cryo EM
    
  • 8eok – hCC3 β+α’ chains + inhibitor protein + Factor Xa – Cryo EM
    
  • 5foa, 5f08, 2icf, 2wii – hCC3 α+β chains + protein
    
  • 3g6j, 6ehg – hCC3 α+β chains + antibody
    
  • 5o35 – hCC3 α chain + complement factor H
    
  • 5o32 – hCC3 α chain + complement factor I
    
  • 2xwb – hCC3 α+β chains + complement factor B + complement factor D
    
  • 2xwj – hCC3 α+β chains (mutant) + complement factor B
    
  • 5nbq – hCC3 α chain + complement factor B
    
  • 5fo8 – hCC3 α chain + membrane cofactor protein
    
  • 6rur – hCC3 α+β chains + complement factor H + complement inhibitor
    
  • 3l5n, 3ohx – hCC3 α+β chains + protein inhibitor
    
  • 2win – hCC3 α+β chains + complement factor B BB fragment + protein inhibitor
    
  • 7qiv – hCC3 α+β chains + nanobody
    
  • 7tv9 – hCC3 α+β chains + APL-1030
    
  • 7akk – hCC3 α+β chains + integrin
    
  • 6xzu – mCC3 C-terminal + nanobody - mouse
    
• Complement C3c
  • 2a74 – hCC3
    
  • 2qki – hCC3 + compstatin
    
  • 3l3o, 3nms – hCC3 + staphylococcal complement inhibitor
    
  • 2ice – hCC3 α+β chains + protein CRIG
    
  • 3t4a – hCC3 α+β chains + fibrinogen-binding protein
    
• Complement C3d
  • 6rmt – hCC3
    
  • 1c3d – hCC3 (mutant)
    
  • 1w2s, 3oed – hCC3 1-2 sushi domains + complement receptor type 2 precursor
    
  • 2gox, 3d5r, 3d5s – hCC3 α chain fragment + fibrinogen-binding protein
    
  • 2noj – hCC3 α chain fragment (mutant) + EFB homologous protein
    
  • 6rmu – hCC3 + IGG-binding protein Sbi
    
  • 2wy7, 2wy8 – hCC3 α chain fragment (mutant) + IGG-binding protein
    
  • 3oxu – hCC3 α chain fragment (mutant) + HF protein
    
  • 4m76 – hCC3 α chain fragment (mutant) + integrin α-M
    
  • 2xqw – hCC3 + complement factor H 19-20 sushi domains
    
  • 3rj3 – hCC3 α chain fragment + complement factor H-related protein
    
  • 5mt0, 5mt4, 5tca, 5tcc, 5fbe, 5fbi, 5fck – hCC3 + inhibitor
    
  • 7ue9 – hCC3 + antibody
    
  • 7pi6 – hCC3 + ISG65
    
  • 1qqf – rCC3 G fragment - rat
    
  • 1qsj – rCC3 G fragment (mutant)
    
  • 5fcr – mCC3
    

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman