2z61: Difference between revisions

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{{Seed}}
[[Image:2z61.png|left|200px]]


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==Crystal structure of MJ0684 from Methanococcus jannaschii reveals its similarity in the active site to kynurenine aminotransferases==
The line below this paragraph, containing "STRUCTURE_2z61", creates the "Structure Box" on the page.
<StructureSection load='2z61' size='340' side='right'caption='[[2z61]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2z61]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_DSM_2661 Methanocaldococcus jannaschii DSM 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z61 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z61 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
{{STRUCTURE_2z61|  PDB=2z61  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z61 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z61 OCA], [https://pdbe.org/2z61 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z61 RCSB], [https://www.ebi.ac.uk/pdbsum/2z61 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z61 ProSAT]</span></td></tr>
 
</table>
===Crystal structure of MJ0684 from Methanococcus jannaschii reveals its similarity in the active site to kynurenine aminotransferases===
== Function ==
 
[https://www.uniprot.org/uniprot/MFNC_METJA MFNC_METJA] Catalyzes the transamination reaction between 4-(hydroxymethyl)-2-furancarboxaldehyde phosphate (4-HFC-P) and alanine to produce pyruvate and 5-(aminomethyl)-3-furanmethanol phosphate (F1-P), the precursor for the furan moiety in methanofuran.<ref>PMID:24977328</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2Z61 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z61 OCA].  
Check<jmol>
[[Category: Aspartate transaminase]]
  <jmolCheckbox>
[[Category: Methanocaldococcus jannaschii]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z6/2z61_consurf.spt"</scriptWhenChecked>
[[Category: Yang, J K.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Amino acid aminotransferase]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Cytoplasm]]
  </jmolCheckbox>
[[Category: Kynurenine aminotransferase]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z61 ConSurf].
[[Category: Mj0684]]
<div style="clear:both"></div>
[[Category: Pyridoxal phosphate]]
== References ==
 
<references/>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 03:00:01 2009''
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii DSM 2661]]
[[Category: Yang JK]]

Latest revision as of 22:30, 26 March 2025

Crystal structure of MJ0684 from Methanococcus jannaschii reveals its similarity in the active site to kynurenine aminotransferases

2z61, resolution 2.20Å

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