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==Structural characterization of the interaction of colicin A, colicin N, and TolB with TolAIII translocon==
==Structural characterization of the interaction of colicin A, colicin N, and TolB with TolAIII translocon==
<StructureSection load='3qdp' size='340' side='right' caption='[[3qdp]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='3qdp' size='340' side='right'caption='[[3qdp]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3qdp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QDP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QDP FirstGlance]. <br>
<table><tr><td colspan='2'>[[3qdp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QDP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QDP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MLZ:N-METHYL-LYSINE'>MLZ</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene>, <scene name='pdbligand=MLZ:N-METHYL-LYSINE'>MLZ</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qdr|3qdr]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qdp OCA], [https://pdbe.org/3qdp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qdp RCSB], [https://www.ebi.ac.uk/pdbsum/3qdp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qdp ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tolA, cim, excC, lky, b0739, JW0729 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qdp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qdp OCA], [http://pdbe.org/3qdp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3qdp RCSB], [http://www.ebi.ac.uk/pdbsum/3qdp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3qdp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/TOLA_ECOLI TOLA_ECOLI]] Involved in the TonB-independent uptake of group A colicins (colicins A, E1, E2, E3, and K). Necessary for the colicins to reach their respective targets after initial binding to the bacteria. Also involved in the translocation of bacteriophage DNA.  
[https://www.uniprot.org/uniprot/TOLA_ECOLI TOLA_ECOLI] Involved in the TonB-independent uptake of group A colicins (colicins A, E1, E2, E3, and K). Necessary for the colicins to reach their respective targets after initial binding to the bacteria. Also involved in the translocation of bacteriophage DNA.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Li, C]]
[[Category: Large Structures]]
[[Category: Cola]]
[[Category: Li C]]
[[Category: Colicin]]
[[Category: Coln]]
[[Category: Methylation]]
[[Category: Protein transport]]
[[Category: Tola]]
[[Category: Tolb]]
[[Category: Translocation]]