8v2g: Difference between revisions
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New page: '''Unreleased structure''' The entry 8v2g is ON HOLD Authors: Description: Category: Unreleased Structures |
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==Cryo-EM structure of the KCa2.2 channel in apo state== | |||
<StructureSection load='8v2g' size='340' side='right'caption='[[8v2g]], [[Resolution|resolution]] 3.18Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8v2g]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8V2G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8V2G FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.18Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8v2g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8v2g OCA], [https://pdbe.org/8v2g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8v2g RCSB], [https://www.ebi.ac.uk/pdbsum/8v2g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8v2g ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/KCNN2_RAT KCNN2_RAT] Forms a voltage-independent potassium channel activated by intracellular calcium. Activation is followed by membrane hyperpolarization. Thought to regulate neuronal excitability by contributing to the slow component of synaptic afterhyperpolarization. The channel is blocked by apamin. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rattus norvegicus]] | |||
[[Category: Nam YW]] | |||
[[Category: Zhang M]] | |||
Latest revision as of 05:15, 23 April 2025
Cryo-EM structure of the KCa2.2 channel in apo state
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