Dynactin: Difference between revisions

Latest revision as of 09:12, 4 May 2025

spinqualitylabelsall models

Dynactin subunit 1 CAP-Gly domain (magenta and yellow) complex with the C-terminal domain of human EB1 (cyan and green) and chloride ion 2hl5

Drag the structure with the mouse to rotate

Export Animated Image Print3D

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

[1] Gill SR, Schroer TA, Szilak I, Steuer ER, Sheetz MP, Cleveland DW. Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J Cell Biol. 1991 Dec;115(6):1639-50. PMID:1836789

[2] Puls I, Jonnakuty C, LaMonte BH, Holzbaur EL, Tokito M, Mann E, Floeter MK, Bidus K, Drayna D, Oh SJ, Brown RH Jr, Ludlow CL, Fischbeck KH. Mutant dynactin in motor neuron disease. Nat Genet. 2003 Apr;33(4):455-6. Epub 2003 Mar 10. PMID:12627231 doi:10.1038/ng1123

[3] Honnappa S, Okhrimenko O, Jaussi R, Jawhari H, Jelesarov I, Winkler FK, Steinmetz MO. Key interaction modes of dynamic +TIP networks. Mol Cell. 2006 Sep 1;23(5):663-71. PMID:16949363 doi:10.1016/j.molcel.2006.07.013

[1]

[2]

[3]

@@ Line 1: / Line 1: @@
 <StructureSection load='2hl5' size='350' side='right' scene='44/444636/Cv/1' caption='Dynactin subunit 1 CAP-Gly domain (magenta and yellow) complex with the C-terminal domain of human EB1 (cyan and green) and chloride ion [[2hl5]]'>
+__TOC__
 == Function ==
@@ Line 12: / Line 14: @@
 == Structural highlights ==
 <scene name='44/444636/Cv/3'>Dynactin subunit 1 CAP-Gly domain with the C-terminal domain of human EB1</scene> ([[2hl5]]).<ref>PMID:16949363</ref>
-</StructureSection>
 == 3D Structures of Dynactin ==
+[[Dynactin 3D structures]]
 Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
-[[2coy]], [[2mpx]] - hDCTN subunit 1 CAP-Gly domain – human – NMR<br />
-[[2hkn]] - hDCTN subunit 1 CAP-Gly domain<br />
-[[3e2u]] – hDCTN subunit 1 CAP-Gly domain + CAP-Gly domain-containing protein linker 1<br />
-[[2hkq]], [[2hl3]], [[1txq]] - hDCTN subunit 1 CAP-Gly domain + microtubule-associated protein C-terminal<br />
-[[2hqh]] - hDCTN subunit 1 CAP-Gly domain + restin 2nd zinc finger domain<br />
-[[2hl5]], [[3tq7]] - hDCTN subunit 1 CAP-Gly domain (mutant) + microtubule-associated protein C-terminal<br />
-[[2m02]] - DCTN subunit 1 CAP-Gly domain – rat – NMR<br />
-[[3tv0]] - hDCTN subunit 6<br />
-[[5adx]] – pDCTN subunits 2,3,5,6 + actin-related protein + actin + capping protein – pig – CryoEM<br />
-[[5afu]], [[5nw4]] – pDCTN subunits 2,3,5,6 + dynein tail + capping protein  – CryoEM<br />
-[[4rfx]] - DCTN subunit 1 coiled coil 1 domain (mutant) - chicken<br />
 == References ==
 <references/>
+</StructureSection>
 [[Category:Topic Page]]

Dynactin: Difference between revisions

Latest revision as of 09:12, 4 May 2025

Contents

Function

Disease

Structural highlights

3D Structures of Dynactin

References

Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools