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[[Image:3ba6.jpg|left|200px]]<br /><applet load="3ba6" size="350" color="white" frame="true" align="right" spinBox="true"
caption="3ba6, resolution 2.8&Aring;" />
'''Structure of the Ca2E1P phosphoenzyme intermediate of the SERCA Ca2+-ATPase'''<br />


==About this Structure==
==Structure of the Ca2E1P phosphoenzyme intermediate of the SERCA Ca2+-ATPase==
3BA6 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=K:'>K</scene> and <scene name='pdbligand=AN2:'>AN2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BA6 OCA].  
<StructureSection load='3ba6' size='340' side='right'caption='[[3ba6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
[[Category: Calcium-transporting ATPase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[3ba6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3BA6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3BA6 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AN2:AMP+PHOSPHORAMIDATE'>AN2</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PHD:ASPARTYL+PHOSPHATE'>PHD</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ba6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ba6 OCA], [https://pdbe.org/3ba6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ba6 RCSB], [https://www.ebi.ac.uk/pdbsum/3ba6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ba6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ba/3ba6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ba6 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[ATPase 3D structures|ATPase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
[[Category: Single protein]]
[[Category: Gyrup C]]
[[Category: Gyrup, C.]]
[[Category: Moller JV]]
[[Category: Moller, J V.]]
[[Category: Morth JP]]
[[Category: Morth, J P.]]
[[Category: Nissen P]]
[[Category: Nissen, P.]]
[[Category: Olesen C]]
[[Category: Olesen, C.]]
[[Category: Oxvig C]]
[[Category: Oxvig, C.]]
[[Category: Picard M]]
[[Category: Picard, M.]]
[[Category: Winther AML]]
[[Category: Winther, A M.L.]]
[[Category: AN2]]
[[Category: CA]]
[[Category: K]]
[[Category: alternative splicing]]
[[Category: aspartyl-phosphoanhydride]]
[[Category: atp-binding]]
[[Category: calcium]]
[[Category: calcium transport]]
[[Category: endoplasmic reticulum]]
[[Category: hydrolase]]
[[Category: ion transport]]
[[Category: magnesium]]
[[Category: membrane protein]]
[[Category: metal-binding]]
[[Category: nucleotide-binding]]
[[Category: p-type atpase]]
[[Category: phosphoenzyme]]
[[Category: phosphorylation]]
[[Category: sarcoplasmic reticulum]]
[[Category: transmembrane]]
[[Category: transport]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 19:04:28 2008''
Retrieved from "https://proteopedia.org/3ba6"