9jdu: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
New page: '''Unreleased structure''' The entry 9jdu is ON HOLD Authors: Huang, Y.-Y., Guo, L., Luo, H.-B. Description: The crystal structure of PDE10A complexed with inhibitor 2061 [[Category: U...
 
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
 
(2 intermediate revisions by the same user not shown)
Line 1: Line 1:
'''Unreleased structure'''


The entry 9jdu is ON HOLD
==The crystal structure of PDE10A complexed with inhibitor 2061==
 
<StructureSection load='9jdu' size='340' side='right'caption='[[9jdu]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
Authors: Huang, Y.-Y., Guo, L., Luo, H.-B.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9jdu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JDU FirstGlance]. <br>
Description: The crystal structure of PDE10A complexed with inhibitor 2061
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3000176&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EBE:ethyl+2-[1-[4-[2-(diethylaminomethylamino)ethanoyl]quinolin-2-yl]azetidin-3-yl]imidazo[1,2-a]pyridine-3-carboxylate'>A1EBE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Guo, L]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jdu OCA], [https://pdbe.org/9jdu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jdu RCSB], [https://www.ebi.ac.uk/pdbsum/9jdu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jdu ProSAT]</span></td></tr>
[[Category: Luo, H.-B]]
</table>
[[Category: Huang, Y.-Y]]
== Function ==
[https://www.uniprot.org/uniprot/PDE10_HUMAN PDE10_HUMAN] Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate.<ref>PMID:17389385</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Guo L]]
[[Category: Huang Y-Y]]
[[Category: Luo H-B]]
Retrieved from "https://proteopedia.org/9jdu"