6iy2: Difference between revisions

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<SX load='6iy2' size='340' side='right' viewer='molstar' caption='[[6iy2]], [[Resolution|resolution]] 3.47&Aring;' scene=''>
<SX load='6iy2' size='340' side='right' viewer='molstar' caption='[[6iy2]], [[Resolution|resolution]] 3.47&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6iy2]] is a 11 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IY2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IY2 FirstGlance]. <br>
<table><tr><td colspan='2'>[[6iy2]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus], [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IY2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6IY2 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.47&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6iy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iy2 OCA], [http://pdbe.org/6iy2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6iy2 RCSB], [http://www.ebi.ac.uk/pdbsum/6iy2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6iy2 ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6iy2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6iy2 OCA], [https://pdbe.org/6iy2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6iy2 RCSB], [https://www.ebi.ac.uk/pdbsum/6iy2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6iy2 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/SNF2_YEAST SNF2_YEAST]] Involved in transcriptional activation. Catalytic component of the SWI/SNF complex, an ATP-dependent chromatin-remodeling complex, which is required for the positive and negative regulation of gene expression of a large number of genes. It changes chromatin structure by altering DNA-histone contacts within a nucleosome, leading eventually to a change in nucleosome position, thus facilitating or repressing binding of gene-specific transcription factors. [[http://www.uniprot.org/uniprot/H4_XENLA H4_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.  
[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Helicase 3D structures|Helicase 3D structures]]
*[[Histone 3D structures|Histone 3D structures]]
*[[Histone 3D structures|Histone 3D structures]]
== References ==
== References ==
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</SX>
</SX>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chen, Z]]
[[Category: Mus musculus]]
[[Category: Li, M]]
[[Category: Saccharomyces cerevisiae S288C]]
[[Category: Li, X]]
[[Category: Xenopus laevis]]
[[Category: Liu, X]]
[[Category: Chen Z]]
[[Category: Xia, X]]
[[Category: Li M]]
[[Category: Chromatin remodeling]]
[[Category: Li X]]
[[Category: Complex]]
[[Category: Liu X]]
[[Category: Dna binding protein]]
[[Category: Xia X]]
[[Category: Gene regulation]]
[[Category: Nucleosome]]
[[Category: Structural protein-hydrolase-dna complex]]
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