9ehs: Difference between revisions
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==Structure of a human adenosine A3 receptor complex bound to the covalent antagonist LUF7602== | |||
<StructureSection load='9ehs' size='340' side='right'caption='[[9ehs]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9ehs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EHS FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1BII:4-({3-[(5S)-8-methoxy-2,4-dioxo-3-propyl-3,4-dihydropyrido[2,1-f]purin-1(2H)-yl]propyl}carbamoyl)benzene-1-sulfonyl+fluoride'>A1BII</scene></td></tr> | ||
[[Category: Glukhova | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ehs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ehs OCA], [https://pdbe.org/9ehs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ehs RCSB], [https://www.ebi.ac.uk/pdbsum/9ehs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ehs ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Thal | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/AA3R_HUMAN AA3R_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase (PubMed:8234299).<ref>PMID:8234299</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Glukhova A]] | |||
[[Category: Mobbs JI]] | |||
[[Category: Thal DM]] | |||
[[Category: Zhang L]] | |||
Latest revision as of 06:11, 20 August 2025
Structure of a human adenosine A3 receptor complex bound to the covalent antagonist LUF7602
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