9ig2: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry 9ig2 is ON HOLD until Paper Publication~~

==Crystal structure of human aldehyde dehydrogenase 3 A1 (ALDH3A1) bound to allyl-isothiocyanate==

~~Authors: Schwartz, M., Neiers, F.~~

== Structural highlights ==

<table><tr><td colspan='2'>[[9ig2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IG2 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9IG2 FirstGlance].

~~Description:~~ Crystal structure of human aldehyde dehydrogenase 3 A1 (ALDH3A1) bound to allyl-isothiocyanate

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9AI:N-PROP-2-EN-1-YLTHIOFORMAMIDE'>9AI</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>

[[Category: ~~Schwartz, M~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9ig2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ig2 OCA], [https://pdbe.org/9ig2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ig2 RCSB], [https://www.ebi.ac.uk/pdbsum/9ig2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ig2 ProSAT]</td></tr>

[[Category: Neiers, F]]

</table>

== Function ==

[https://www.uniprot.org/uniprot/AL3A1_HUMAN AL3A1_HUMAN] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Neiers F]]

[[Category: Schwartz M]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9ig2 is ON HOLD  until Paper Publication
+==Crystal structure of human aldehyde dehydrogenase 3 A1 (ALDH3A1) bound to allyl-isothiocyanate==
+<StructureSection load='9ig2' size='340' side='right'caption='[[9ig2]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
-Authors: Schwartz, M., Neiers, F.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9ig2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IG2 FirstGlance]. <br>
-Description: Crystal structure of human aldehyde dehydrogenase 3 A1 (ALDH3A1) bound to allyl-isothiocyanate
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9AI:N-PROP-2-EN-1-YLTHIOFORMAMIDE'>9AI</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-[[Category: Schwartz, M]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ig2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ig2 OCA], [https://pdbe.org/9ig2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ig2 RCSB], [https://www.ebi.ac.uk/pdbsum/9ig2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ig2 ProSAT]</span></td></tr>
-[[Category: Neiers, F]]
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/AL3A1_HUMAN AL3A1_HUMAN] ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. This protein preferentially oxidizes aromatic aldehyde substrates. It may play a role in the oxidation of toxic aldehydes.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Neiers F]]
+[[Category: Schwartz M]]