21fd: Difference between revisions

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'''Unreleased structure'''


The entry 21fd is ON HOLD
==Neutron crystal structure of the apo form of the human Hsp90 N-terminal domain==
 
<StructureSection load='21fd' size='340' side='right'caption='[[21fd]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
Authors: Hirano, Y., Kusaka, K., Ose, T., Kurihara, K., Aburai, K., Saito, J., Tamata, T.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[21fd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=21FD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=21FD FirstGlance]. <br>
Description: Neutron crystal structure of the apo form of the human Hsp90 N-terminal domain
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Neutron Diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=21fd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=21fd OCA], [https://pdbe.org/21fd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=21fd RCSB], [https://www.ebi.ac.uk/pdbsum/21fd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=21fd ProSAT]</span></td></tr>
[[Category: Hirano, Y]]
</table>
[[Category: Kurihara, K]]
== Function ==
[[Category: Tamata, T]]
[https://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref>
[[Category: Aburai, K]]
== References ==
[[Category: Ose, T]]
<references/>
[[Category: Kusaka, K]]
__TOC__
[[Category: Saito, J]]
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Aburai K]]
[[Category: Hirano Y]]
[[Category: Kurihara K]]
[[Category: Kusaka K]]
[[Category: Ose T]]
[[Category: Saito J]]
[[Category: Tamada T]]

Latest revision as of 06:35, 3 June 2026

Neutron crystal structure of the apo form of the human Hsp90 N-terminal domain

21fd, resolution 2.10Å

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