9oss: Difference between revisions

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New page: '''Unreleased structure''' The entry 9oss is ON HOLD Authors: Description: Category: Unreleased Structures
 
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'''Unreleased structure'''


The entry 9oss is ON HOLD
==Structure of human Fab HB31 in complex with influenza H1N1 A/Solomon Island/3/2006 hemagglutinin==
 
<StructureSection load='9oss' size='340' side='right'caption='[[9oss]], [[Resolution|resolution]] 2.76&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9oss]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Influenza_A_virus Influenza A virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9OSS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9OSS FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.76&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9oss FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9oss OCA], [https://pdbe.org/9oss PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9oss RCSB], [https://www.ebi.ac.uk/pdbsum/9oss PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9oss ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A0G2RTI0_9INFA A0A0G2RTI0_9INFA] Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles through clathrin-dependent endocytosis and about one third through a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.[ARBA:ARBA00059860][RuleBase:RU003324]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Influenza A virus]]
[[Category: Large Structures]]
[[Category: Lv H]]
[[Category: Pholcharee T]]
[[Category: Wu NC]]
Retrieved from "https://proteopedia.org/9oss"