9s2f: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "9s2f" [edit=sysop:move=sysop] |
No edit summary |
||
| (2 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Human debranched intron spliceosome (DIS)== | |||
<StructureSection load='9s2f' size='340' side='right'caption='[[9s2f]], [[Resolution|resolution]] 3.14Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9s2f]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9S2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9S2F FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.14Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9s2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9s2f OCA], [https://pdbe.org/9s2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9s2f RCSB], [https://www.ebi.ac.uk/pdbsum/9s2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9s2f ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/DHX35_HUMAN DHX35_HUMAN] Acts as a co-sensor in RIGI-mediated antiviral innate immunity (PubMed:39037956). Enhances RIGI recognition of viral nucleic acids and interacts with RIGI and MAVS to form a signaling complex which triggers downstream signaling cascades that lead to the induction of type I interferons and pro-inflammatory cytokines during the antiviral innate immune response (PubMed:39037956).<ref>PMID:39037956</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Boreikaite V]] | |||
[[Category: Plaschka C]] | |||
[[Category: Vorlaender MK]] | |||
Latest revision as of 20:20, 29 July 2026
Human debranched intron spliceosome (DIS)
| ||||||||||||
