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==The role of I87 of CYP158A2 in oxidative coupling reaction==
==The role of I87 of CYP158A2 in oxidative coupling reaction==
<StructureSection load='3tzo' size='340' side='right' caption='[[3tzo]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
<StructureSection load='3tzo' size='340' side='right'caption='[[3tzo]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3tzo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TZO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TZO FirstGlance]. <br>
<table><tr><td colspan='2'>[[3tzo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TZO FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1s1f|1s1f]], [[1se6|1se6]], [[1t93|1t93]], [[2d09|2d09]], [[2dkk|2dkk]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=SPM:SPERMINE'>SPM</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SCO1207 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1902 Streptomyces coelicolor])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tzo OCA], [https://pdbe.org/3tzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tzo RCSB], [https://www.ebi.ac.uk/pdbsum/3tzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tzo ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tzo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tzo RCSB], [http://www.ebi.ac.uk/pdbsum/3tzo PDBsum]</span></td></tr>
</table>
<table>
== Function ==
[https://www.uniprot.org/uniprot/C1582_STRCO C1582_STRCO] Catalyze oxidative C-C coupling reaction to polymerize flaviolin and form highly conjugated pigments which protect the soil bacterium from deleterious effects of UV irradiation (three isomers of biflaviolin and one triflaviolin).<ref>PMID:15659395</ref> <ref>PMID:16239228</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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The role of Ile87 of CYP158A2 in oxidative coupling reaction.,Zhao B, Bellamine A, Lei L, Waterman MR Arch Biochem Biophys. 2011 Dec 19. PMID:22203090<ref>PMID:22203090</ref>
The role of Ile87 of CYP158A2 in oxidative coupling reaction.,Zhao B, Bellamine A, Lei L, Waterman MR Arch Biochem Biophys. 2011 Dec 19. PMID:22203090<ref>PMID:22203090</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 3tzo" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Streptomyces coelicolor]]
[[Category: Streptomyces coelicolor]]
[[Category: Waterman, M R.]]
[[Category: Waterman MR]]
[[Category: Zhao, B.]]
[[Category: Zhao B]]
[[Category: Cyp158a2]]
[[Category: Monooxygenase]]
[[Category: Oxidoreductase]]
[[Category: P450]]
[[Category: Phenolic coupling reaction]]
Retrieved from "https://proteopedia.org/3tzo"