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==Crystal structure of NAD+-reducing [NiFe]-hydrogenase in the H2-reduced state==
==Crystal structure of NAD+-reducing [NiFe]-hydrogenase in the H2-reduced state==
<StructureSection load='5xfa' size='340' side='right' caption='[[5xfa]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='5xfa' size='340' side='right'caption='[[5xfa]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5xfa]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Hydrogenophilus_thermoluteolus Hydrogenophilus thermoluteolus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XFA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XFA FirstGlance]. <br>
<table><tr><td colspan='2'>[[5xfa]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Hydrogenophilus_thermoluteolus Hydrogenophilus thermoluteolus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XFA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XFA FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FCO:CARBONMONOXIDE-(DICYANO)+IRON'>FCO</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5xf9|5xf9]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FCO:CARBONMONOXIDE-(DICYANO)+IRON'>FCO</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xfa OCA], [http://pdbe.org/5xfa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xfa RCSB], [http://www.ebi.ac.uk/pdbsum/5xfa PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xfa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xfa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xfa OCA], [https://pdbe.org/5xfa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xfa RCSB], [https://www.ebi.ac.uk/pdbsum/5xfa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xfa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A077L6X8_HYDTE A0A077L6X8_HYDTE]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Hydrogenophilus thermoluteolus]]
[[Category: Hydrogenophilus thermoluteolus]]
[[Category: Higuchi, Y]]
[[Category: Large Structures]]
[[Category: Hirota, S]]
[[Category: Higuchi Y]]
[[Category: Igarashi, Y]]
[[Category: Hirota S]]
[[Category: Ikeda, Y]]
[[Category: Igarashi Y]]
[[Category: Ishii, M]]
[[Category: Ikeda Y]]
[[Category: Nakagawa, H]]
[[Category: Ishii M]]
[[Category: Nakashima, H]]
[[Category: Nakagawa H]]
[[Category: Nishihara, H]]
[[Category: Nakashima H]]
[[Category: Ogo, S]]
[[Category: Nishihara H]]
[[Category: Shomura, Y]]
[[Category: Ogo S]]
[[Category: Tai, H]]
[[Category: Shomura Y]]
[[Category: Taketa, M]]
[[Category: Tai H]]
[[Category: Yoon, K S]]
[[Category: Taketa M]]
[[Category: Fe-]]
[[Category: Yoon KS]]
[[Category: Hydrogenase]]
[[Category: Ni-fe]]
[[Category: Oxidoreductase]]

Latest revision as of 12:46, 13 August 2026

Crystal structure of NAD+-reducing [NiFe]-hydrogenase in the H2-reduced state

5xfa, resolution 2.70Å

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