9x1f: Difference between revisions
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New page: '''Unreleased structure''' The entry 9x1f is ON HOLD Authors: Description: Category: Unreleased Structures |
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==NMR structure of the membrane-active toxin U11-MYRTX-Tb1a from ant Tetramorium bicarinatum in DPC micelle== | |||
<StructureSection load='9x1f' size='340' side='right'caption='[[9x1f]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9x1f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Tetramorium_bicarinatum Tetramorium bicarinatum]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9X1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9X1F FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9x1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9x1f OCA], [https://pdbe.org/9x1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9x1f RCSB], [https://www.ebi.ac.uk/pdbsum/9x1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9x1f ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TX11A_TETBN TX11A_TETBN] Neurotoxin that causes irreversible rapid flaccid paralysis in blowflies and honeybees upon intrathoracic injection (PubMed:37888631). Causes a quick and irreversible cytolytic effect (at 10 uM) indicating it possibly acts as a pore-forming peptide (PubMed:38786948). Shows only weak effect on aphids (A.pisum) at high doses 24 hours post intrathoracic injection (PubMed:37888631). In vitro, is not cytotoxic on the dipteran S2 Drosophila embryonic cell line (PubMed:37888631).<ref>PMID:37888631</ref> <ref>PMID:38786948</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Tetramorium bicarinatum]] | |||
[[Category: Chernaya EM]] | |||
[[Category: Gorelov SA]] | |||
[[Category: Mironov PA]] | |||
[[Category: Shenkarev ZO]] | |||