Sandbox4: Difference between revisions
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Name: Jamal Salah and Vishwa Shah! | |||
{{ | LKT: | ||
It's alpha and beta SUBUNITS (2 of each). Say something about the secondary elements (ie 5 alpha helices and 2 beta strands) | |||
I see problems with greek letters on the JMol, so best to write out alpha and beta. Why did you highlight His which is not hydrophobic? | |||
{{STRUCTURE_101m | PDB=101m | SCENE= }} | |||
== '''Deoxyhemoglobin''' == | |||
The major oxygen-binding molecule in man, responsible for binding oxygen in the lung and transporting it to the tissues by means of circulation. | |||
Hemoglobin is an iron Fe chelate tightly binding one Fe where it carries a 2+ charge(ferrous ion). If no oxygen molecule is bound it is called deoxyheemoglobin. Deoxyhemoglobin is a tetramer of <scene name='Sandbox4/Alpha2beta2/3'>alpha and beta strands</scene>. The <scene name='Sandbox4/Overall_structure/2'>Overall Structure</scene> is shown here. Deoxyhemoglobin contanis a <scene name='Sandbox4/Heme_group/3'>Heme group</scene>, as well as an ampipathic surface. The | |||
<scene name='Sandbox4/Polar_helix/1'>polar</scene> chain of HIS is highlighted in blue. The <scene name='Sandbox4/Nonpolar_side/1'>nonpolar</scene> chain of PHE is highlighted in green. | |||
Reference: | |||
1).[[ http://www.medcyclopaedia.com/library/topics/volume_i/d/deoxyhaemoglobin.aspx]] | |||
2) http://www.proteopedia.org/wiki/index.php/Hemoglobin | |||
Latest revision as of 19:54, 17 March 2009
This sandbox is in use until June 1, 2009 for UMass Chemistry 490a. Others please do not edit this page. Thanks!'
Name: Jamal Salah and Vishwa Shah!
LKT: It's alpha and beta SUBUNITS (2 of each). Say something about the secondary elements (ie 5 alpha helices and 2 beta strands) I see problems with greek letters on the JMol, so best to write out alpha and beta. Why did you highlight His which is not hydrophobic?
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| 101m, resolution 2.07Å (default scene) | |||||||||||||
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| Ligands: | HEM, NBN, SO4 | ||||||||||||
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Deoxyhemoglobin
The major oxygen-binding molecule in man, responsible for binding oxygen in the lung and transporting it to the tissues by means of circulation. Hemoglobin is an iron Fe chelate tightly binding one Fe where it carries a 2+ charge(ferrous ion). If no oxygen molecule is bound it is called deoxyheemoglobin. Deoxyhemoglobin is a tetramer of alpha and beta strands. The Overall Structure is shown here. Deoxyhemoglobin contanis a Heme group, as well as an ampipathic surface. The polar chain of HIS is highlighted in blue. The nonpolar chain of PHE is highlighted in green.
Reference:
1).[[ https://www.medcyclopaedia.com/library/topics/volume_i/d/deoxyhaemoglobin.aspx]]
