1t6s: Difference between revisions

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New page: left|200px<br /><applet load="1t6s" size="450" color="white" frame="true" align="right" spinBox="true" caption="1t6s, resolution 1.95Å" /> '''Crystal structure of...
 
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[[Image:1t6s.jpg|left|200px]]<br /><applet load="1t6s" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1t6s, resolution 1.95&Aring;" />
'''Crystal structure of a conserved hypothetical protein from Chlorobium tepidum'''<br />


==Overview==
==Crystal structure of a conserved hypothetical protein from Chlorobium tepidum==
Structural maintenance of chromosome (SMC) proteins are essential in, chromosome condensation and interact with non-SMC proteins in eukaryotes, and with segregation and condensation proteins (ScpA and ScpB) in, prokaryotes. The highly conserved gene in Chlorobium tepidum gi 21646405, encodes ScpB (ScpB_ChTe). The high resolution crystal structure of, ScpB_ChTe shows that the monomeric structure consists of two similarly, shaped globular domains composed of three helices sided by beta-strands [a, winged helix-turn-helix (HTH)], a motif observed in the C-terminal domain, of Scc1, a functionally related eukaryotic ScpA homolog, as well as in, many DNA binding proteins.
<StructureSection load='1t6s' size='340' side='right'caption='[[1t6s]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1t6s]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlorobaculum_tepidum_TLS Chlorobaculum tepidum TLS]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1T6S FirstGlance]. <br>
1T6S is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Chlorobium_tepidum_tls Chlorobium tepidum tls] with NO3 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1T6S OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1t6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1t6s OCA], [https://pdbe.org/1t6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1t6s RCSB], [https://www.ebi.ac.uk/pdbsum/1t6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1t6s ProSAT], [https://www.topsan.org/Proteins/BSGC/1t6s TOPSAN]</span></td></tr>
Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning., Kim JS, Shin DH, Pufan R, Huang C, Yokota H, Kim R, Kim SH, Proteins. 2006 Feb 1;62(2):322-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16294331 16294331]
</table>
[[Category: Chlorobium tepidum tls]]
== Function ==
[[Category: Single protein]]
[https://www.uniprot.org/uniprot/Q8KF54_CHLTE Q8KF54_CHLTE] Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity).
[[Category: BSGC, Berkeley.Structural.Genomics.Center.]]
== Evolutionary Conservation ==
[[Category: Kim, J.S.]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Kim, R.]]
Check<jmol>
[[Category: Kim, S.H.]]
  <jmolCheckbox>
[[Category: Shin, D.H.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/t6/1t6s_consurf.spt"</scriptWhenChecked>
[[Category: NO3]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: a winged helix-turn-helix]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: berkeley structural genomics center]]
  </jmolCheckbox>
[[Category: bsgc structure funded by nih]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1t6s ConSurf].
[[Category: protein structure initiative]]
<div style="clear:both"></div>
[[Category: psi]]
__TOC__
[[Category: structural genomics]]
</StructureSection>
 
[[Category: Chlorobaculum tepidum TLS]]
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 01:46:01 2007''
[[Category: Large Structures]]
[[Category: Kim JS]]
[[Category: Kim R]]
[[Category: Kim SH]]
[[Category: Shin DH]]

Latest revision as of 08:36, 14 February 2024

Crystal structure of a conserved hypothetical protein from Chlorobium tepidum

1t6s, resolution 1.95Å

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