1p1y: Difference between revisions

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New page: left|200px<br /><applet load="1p1y" size="450" color="white" frame="true" align="right" spinBox="true" caption="1p1y, resolution 2.10Å" /> '''Crystal structure of...
 
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[[Image:1p1y.gif|left|200px]]<br /><applet load="1p1y" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1p1y, resolution 2.10&Aring;" />
'''Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)'''<br />


==Overview==
==Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)==
DNA has proved to be a versatile material for the rational design and, assembly of nanometer scale objects. Here we report the crystal structure, of a continuous three-dimensional DNA lattice formed by the self-assembly, of a DNA 13-mer. The structure consists of stacked layers of parallel, helices with adjacent layers linked through parallel-stranded base, pairing. The hexagonal lattice geometry contains solvent channels that, appear large enough to allow 3'-linked guest molecules into the crystal., We have successfully used these parallel base pairs to design and produce, crystals with greatly enlarged solvent channels. This lattice may have, applications as a molecular scaffold for structure determination of guest, molecules, as a molecular sieve, or in the assembly of molecular, electronics. Predictable non-Watson-Crick base pairs, like those described, here, may present a new tool in structural DNA nanotechnology.
<StructureSection load='1p1y' size='340' side='right'caption='[[1p1y]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1p1y]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1P1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1P1Y FirstGlance]. <br>
1P1Y is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ] with MG as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1P1Y OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BRU:5-BROMO-2-DEOXYURIDINE-5-MONOPHOSPHATE'>BRU</scene>, <scene name='pdbligand=CBR:5-BROMO-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>CBR</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1p1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1p1y OCA], [https://pdbe.org/1p1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1p1y RCSB], [https://www.ebi.ac.uk/pdbsum/1p1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1p1y ProSAT]</span></td></tr>
Crystal structure of a continuous three-dimensional DNA lattice., Paukstelis PJ, Nowakowski J, Birktoft JJ, Seeman NC, Chem Biol. 2004 Aug;11(8):1119-26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15324813 15324813]
</table>
[[Category: Protein complex]]
__TOC__
[[Category: Birktoft, J.J.]]
</StructureSection>
[[Category: Nowakowski, J.]]
[[Category: Large Structures]]
[[Category: Paukstelis, P.J.]]
[[Category: Birktoft JJ]]
[[Category: Seeman, N.C.]]
[[Category: Nowakowski J]]
[[Category: MG]]
[[Category: Paukstelis PJ]]
[[Category: continuous three-dimensional dna lattice]]
[[Category: Seeman NC]]
[[Category: parallel-stranded base pairs]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 01:50:06 2007''

Latest revision as of 08:04, 14 February 2024

Crystal structure of a continuous three-dimensional DNA lattice from d(GGACAGATGGGAG)

1p1y, resolution 2.10Å

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