3jz4: Difference between revisions
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New page: '''Unreleased structure''' The entry 3jz4 is ON HOLD Authors: Langendorf, C.G., Key, T.L.G., Fenalti, G., Kan, W.T., Buckle, A.M., Caradoc-Davies, T., Tuck, K.L., Law, R.H.P., Whisstock... |
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==Crystal structure of E. coli NADP dependent enzyme== | |||
<StructureSection load='3jz4' size='340' side='right'caption='[[3jz4]], [[Resolution|resolution]] 2.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3jz4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JZ4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JZ4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jz4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jz4 OCA], [https://pdbe.org/3jz4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jz4 RCSB], [https://www.ebi.ac.uk/pdbsum/3jz4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jz4 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GABD_ECOLI GABD_ECOLI] Catalyzes the NADP(+)-dependent oxidation of succinate semialdehyde to succinate. It appears to be important for nitrogen metabolism under N limitation conditions.<ref>PMID:20174634</ref> <ref>PMID:7011797</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jz/3jz4_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3jz4 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Aldehyde dehydrogenase 3D structures|Aldehyde dehydrogenase 3D structures]] | |||
*[[Succinate-semialdehyde dehydrogenase|Succinate-semialdehyde dehydrogenase]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Buckle AM]] | |||
[[Category: Caradoc-Davies T]] | |||
[[Category: Fenalti G]] | |||
[[Category: Kan WT]] | |||
[[Category: Key TLG]] | |||
[[Category: Langendorf CG]] | |||
[[Category: Law RHP]] | |||
[[Category: Tuck KL]] | |||
[[Category: Whisstock JC]] | |||
