2wqk: Difference between revisions

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{{Seed}}
[[Image:2wqk.jpg|left|200px]]


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==Crystal Structure of Sure Protein from Aquifex aeolicus==
The line below this paragraph, containing "STRUCTURE_2wqk", creates the "Structure Box" on the page.
<StructureSection load='2wqk' size='340' side='right'caption='[[2wqk]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2wqk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2phj 2phj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WQK FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2wqk|  PDB=2wqk  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wqk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wqk OCA], [https://pdbe.org/2wqk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wqk RCSB], [https://www.ebi.ac.uk/pdbsum/2wqk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wqk ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SURE_AQUAE SURE_AQUAE] Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wq/2wqk_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wqk ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
SurE is a stationary-phase survival protein found in bacteria, eukaryotes and archaea that exhibits a divalent-metal-ion-dependent phosphatase activity and acts as a nucleotidase and polyphosphate phosphohydrolase. The structure of the SurE protein from the hyperthermophile Aquifex aeolicus has been solved at 1.5 A resolution using molecular replacement with one dimer in the asymmetric unit and refined to an R factor of 15.6%. The crystal packing reveals that two dimers assemble to form a tetramer, although gel-filtration chromatography showed the presence of only a dimer in solution. The phosphatase active-site pocket was occupied by sulfate ions from the crystallization medium.


===CRYSTAL STRUCTURE OF SURE PROTEIN FROM AQUIFEX AEOLICUS===
Structure of SurE protein from Aquifex aeolicus VF5 at 1.5 A resolution.,Antonyuk SV, Ellis MJ, Strange RW, Bessho Y, Kuramitsu S, Shinkai A, Yokoyama S, Hasnain SS Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Dec 1;65(Pt, 12):1204-8. Epub 2009 Nov 27. PMID:20054112<ref>PMID:20054112</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
==About this Structure==
</div>
2WQK is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Aquifex_aeolicus Aquifex aeolicus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2phj 2phj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WQK OCA].
<div class="pdbe-citations 2wqk" style="background-color:#fffaf0;"></div>
[[Category: 5'-nucleotidase]]
== References ==
[[Category: Aquifex aeolicus]]
<references/>
[[Category: Antonyuk, S V.]]
__TOC__
[[Category: Bessho, Y.]]
</StructureSection>
[[Category: Ellis, M J.]]
[[Category: Aquifex aeolicus VF5]]
[[Category: Hasnain, S S.]]
[[Category: Large Structures]]
[[Category: Kuramitsu, S.]]
[[Category: Antonyuk SV]]
[[Category: Rsgi , Riken Structural Genomics Proteomics Initiative]]
[[Category: Bessho Y]]
[[Category: Strange, R W.]]
[[Category: Ellis MJ]]
[[Category: Yokoyama, S.]]
[[Category: Hasnain SS]]
[[Category: 3-d structure]]
[[Category: Kuramitsu S]]
[[Category: Hydrolase]]
[[Category: Strange RW]]
[[Category: Mixed alpha/beta protein]]
[[Category: Yokoyama S]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Putative acid phosphatase]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Sure protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 30 09:09:22 2009''

Latest revision as of 10:14, 20 December 2023

Crystal Structure of Sure Protein from Aquifex aeolicus

2wqk, resolution 1.50Å

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