3a7o: Difference between revisions
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New page: '''Unreleased structure''' The entry 3a7o is ON HOLD Authors: Fujioka, Y., Noda, N.N., Inagaki, F. Description: The crystal structure of the coiled-coil domain of Saccharomyces cerevis... |
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The | ==The crystal structure of the coiled-coil domain of Saccharomyces cerevisiae Atg16== | ||
<StructureSection load='3a7o' size='340' side='right'caption='[[3a7o]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3a7o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A7O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A7O FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a7o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a7o OCA], [https://pdbe.org/3a7o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a7o RCSB], [https://www.ebi.ac.uk/pdbsum/3a7o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a7o ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ATG16_YEAST ATG16_YEAST] Stabilizes the ATG5-ATG12 conjugate and mediates the formation of the 350 kDa complex, which is necessary for autophagy. Required for ATG8 localization to the pre-autophagosomal structure.<ref>PMID:8224160</ref> <ref>PMID:8663607</ref> <ref>PMID:10406794</ref> <ref>PMID:11689437</ref> <ref>PMID:11897782</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a7/3a7o_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a7o ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Autophagy-related protein 3D structures|Autophagy-related protein 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Fujioka Y]] | |||
[[Category: Inagaki F]] | |||
[[Category: Noda NN]] | |||
Latest revision as of 14:13, 18 October 2023
The crystal structure of the coiled-coil domain of Saccharomyces cerevisiae Atg16
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