3f01: Difference between revisions

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{{Seed}}
[[Image:3f01.jpg|left|200px]]


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==Crystal Structure of Synaptotagmin I C2A domain with Cu(II)==
The line below this paragraph, containing "STRUCTURE_3f01", creates the "Structure Box" on the page.
<StructureSection load='3f01' size='340' side='right'caption='[[3f01]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3f01]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F01 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F01 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3f01| PDB=3f01 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f01 OCA], [https://pdbe.org/3f01 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f01 RCSB], [https://www.ebi.ac.uk/pdbsum/3f01 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f01 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SYT1_HUMAN SYT1_HUMAN] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f0/3f01_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3f01 ConSurf].
<div style="clear:both"></div>


===Crystal Structure of Synaptotagmin I C2A domain with Cu(II)===
==See Also==
 
*[[Synaptotagmin 3D structures|Synaptotagmin 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3F01 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F01 OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Dakshinamurthy, R.]]
[[Category: Large Structures]]
[[Category: Guo, F.]]
[[Category: Dakshinamurthy R]]
[[Category: Sakon, J.]]
[[Category: Guo F]]
[[Category: Thallapuranam, S K.K.]]
[[Category: Sakon J]]
[[Category: C2a]]
[[Category: Thallapuranam SKK]]
[[Category: Calcium]]
[[Category: Cell junction]]
[[Category: Copper]]
[[Category: Cytoplasmic vesicle]]
[[Category: Glycoprotein]]
[[Category: Lipoprotein]]
[[Category: Membrane]]
[[Category: Metal binding protein]]
[[Category: Metal-binding]]
[[Category: Palmitate]]
[[Category: Phosphoprotein]]
[[Category: Synapse]]
[[Category: Synaptotagmin i]]
[[Category: Transmembrane]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct  7 14:08:46 2009''
Retrieved from "https://proteopedia.org/3f01"