2wab: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
 
(9 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:2wab.png|left|200px]]


<!--
==Structure of an active site mutant of a family two carbohydrate esterase from Clostridium thermocellum in complex with celluohexase==
The line below this paragraph, containing "STRUCTURE_2wab", creates the "Structure Box" on the page.
<StructureSection load='2wab' size='340' side='right'caption='[[2wab]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2wab]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acetivibrio_thermocellus Acetivibrio thermocellus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WAB FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=PRD_900016:beta-cellopentaose'>PRD_900016</scene></td></tr>
{{STRUCTURE_2wab| PDB=2wab |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wab OCA], [https://pdbe.org/2wab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wab RCSB], [https://www.ebi.ac.uk/pdbsum/2wab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wab ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CELE_ACET2 CELE_ACET2] Multifunctional enzyme involved in the degradation of plant cell wall polysaccharides. Displays endoglucanase activity against carboxymethyl cellulose (CMC) and barley beta-glucan (PubMed:3066698, PubMed:1991028). Also catalyzes the deacetylation of acetylated birchwood xylan and glucomannan, with a preference for the latter, and of the synthetic substrate 4-nitrophenyl acetate (4-NPAc) (PubMed:19338387).<ref>PMID:19338387</ref> <ref>PMID:1991028</ref> <ref>PMID:3066698</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wa/2wab_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wab ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF AN ACTIVE SITE MUTANT OF A FAMILY TWO CARBOHYDRATE ESTERASE FROM CLOSTRIDIUM THERMOCELLUM IN COMPLEX WITH CELLUOHEXASE===
==See Also==
 
*[[Glucanase 3D structures|Glucanase 3D structures]]
 
== References ==
==About this Structure==
<references/>
2WAB is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Clostridium_thermocellum Clostridium thermocellum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WAB OCA].
__TOC__
[[Category: Cellulase]]
</StructureSection>
[[Category: Clostridium thermocellum]]
[[Category: Acetivibrio thermocellus]]
[[Category: Bolam, D A.]]
[[Category: Large Structures]]
[[Category: Davies, G J.]]
[[Category: Bolam DN]]
[[Category: Dodson, E J.]]
[[Category: Davies GJ]]
[[Category: Flint, J E.]]
[[Category: Dodson EJ]]
[[Category: Fontes, C M.G A.]]
[[Category: Flint JE]]
[[Category: Gilbert, H J.]]
[[Category: Fontes CMGA]]
[[Category: Goyal, A.]]
[[Category: Gilbert HJ]]
[[Category: Izumi, A.]]
[[Category: Goyal A]]
[[Category: Kolenova, K.]]
[[Category: Izumi A]]
[[Category: Money, V A.]]
[[Category: Kolenova K]]
[[Category: Montainer, C.]]
[[Category: Money VA]]
[[Category: Pinheiro, B A.]]
[[Category: Montainer C]]
[[Category: Pires, V M.R.]]
[[Category: Pinheiro BA]]
[[Category: Prates, J A.M.]]
[[Category: Pires VMR]]
[[Category: Stalbrand, H.]]
[[Category: Prates JAM]]
[[Category: Topakas, E.]]
[[Category: Stalbrand H]]
[[Category: Carbohydrate binding]]
[[Category: Topakas E]]
[[Category: Carbohydrate metabolism]]
[[Category: Cellulase]]
[[Category: Cellulose degradation]]
[[Category: Esterase]]
[[Category: Glycosidase]]
[[Category: Hydrolase]]
[[Category: Plant cell wall degradation]]
[[Category: Polysaccharide degradation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct  7 20:06:15 2009''