2r0d: Difference between revisions

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{{Seed}}
[[Image:2r0d.png|left|200px]]


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==Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor==
The line below this paragraph, containing "STRUCTURE_2r0d", creates the "Structure Box" on the page.
<StructureSection load='2r0d' size='340' side='right'caption='[[2r0d]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2r0d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2R0D FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4IP:INOSITOL-(1,3,4,5)-TETRAKISPHOSPHATE'>4IP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_2r0d|  PDB=2r0d  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2r0d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2r0d OCA], [https://pdbe.org/2r0d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2r0d RCSB], [https://www.ebi.ac.uk/pdbsum/2r0d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2r0d ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor===
== Function ==
 
[https://www.uniprot.org/uniprot/CYH3_MOUSE CYH3_MOUSE] Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF factors through replacement of GDP with GTP.<ref>PMID:18042453</ref>  
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_18042453}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 18042453 is the PubMed ID number.
  <jmolCheckbox>
-->
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/r0/2r0d_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_18042453}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
2R0D is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2R0D OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2r0d ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:18042453</ref><references group="xtra"/>
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Cronin, T C.]]
[[Category: Cronin TC]]
[[Category: Czech, M P.]]
[[Category: Czech MP]]
[[Category: Delprato, A.]]
[[Category: Delprato A]]
[[Category: DiNitto, J P.]]
[[Category: DiNitto JP]]
[[Category: Guilherme, A.]]
[[Category: Gabe Lee MT]]
[[Category: Huang, S.]]
[[Category: Guilherme A]]
[[Category: Lambright, D G.]]
[[Category: Huang S]]
[[Category: Lee, M T.Gabe.]]
[[Category: Lambright DG]]
[[Category: 3-phosphoinositide]]
[[Category: Arf gtpase]]
[[Category: Coiled coil]]
[[Category: Exchange factor]]
[[Category: General receptor for phosphoinositide]]
[[Category: Grp1]]
[[Category: Guanine-nucleotide releasing factor]]
[[Category: Pip3]]
[[Category: Signaling protein]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 09:52:14 2009''

Latest revision as of 09:19, 21 February 2024

Crystal Structure of Autoinhibited Form of Grp1 Arf GTPase Exchange Factor

2r0d, resolution 2.04Å

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