3h6q: Difference between revisions

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{{Seed}}
[[Image:3h6q.jpg|left|200px]]


<!--
==Macrocypin, a beta-trefoil cysteine protease inhibitor==
The line below this paragraph, containing "STRUCTURE_3h6q", creates the "Structure Box" on the page.
<StructureSection load='3h6q' size='340' side='right'caption='[[3h6q]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3h6q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Macrolepiota_procera Macrolepiota procera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H6Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3H6Q FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.643&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3h6q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3h6q OCA], [https://pdbe.org/3h6q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3h6q RCSB], [https://www.ebi.ac.uk/pdbsum/3h6q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3h6q ProSAT]</span></td></tr>
{{STRUCTURE_3h6q|  PDB=3h6q  |  SCENE=  }}
</table>
 
== Function ==
===Macrocypin, a Kunitz type cysteine protease inhibitor===
[https://www.uniprot.org/uniprot/MCP1A_MACPC MCP1A_MACPC] Inhibits papain and cysteine cathepsin endopeptidases, and also inhibits cathepsins B and H, which exhibit both exopeptidase and endopeptidase activities.<ref>PMID:19678836</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
3H6Q is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Macrolepiota_procera Macrolepiota procera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3H6Q OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h6/3h6q_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3h6q ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Macrolepiota procera]]
[[Category: Macrolepiota procera]]
[[Category: Brzin, J.]]
[[Category: Brzin J]]
[[Category: Renko, M.]]
[[Category: Renko M]]
[[Category: Sabotic, J.]]
[[Category: Sabotic J]]
[[Category: Turk, D.]]
[[Category: Turk D]]
[[Category: Beta trefoil]]
[[Category: Cysteine protease inhibitor]]
[[Category: Hydrolase/hydrolase inhibitor complex]]
[[Category: Kunitz type inhibitor]]
[[Category: Macrocypin]]
[[Category: Mycocypin]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 10:35:30 2009''
Retrieved from "https://proteopedia.org/3h6q"